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Conditional astroglial Rictor overexpression induces malignant glioma in mice.
Bashir T, Cloninger C, Artinian N, Anderson L, Bernath A, Holmes B, Benavides-Serrato A, Sabha N, Nishimura RN, Guha A, Gera J. Bashir T, et al. Among authors: holmes b. PLoS One. 2012;7(10):e47741. doi: 10.1371/journal.pone.0047741. Epub 2012 Oct 15. PLoS One. 2012. PMID: 23077666 Free PMC article.
Phosphomimetic substitution of heterogeneous nuclear ribonucleoprotein A1 at serine 199 abolishes AKT-dependent internal ribosome entry site-transacting factor (ITAF) function via effects on strand annealing and results in mammalian target of rapamycin complex 1 (mTORC1) inhibitor sensitivity.
Martin J, Masri J, Cloninger C, Holmes B, Artinian N, Funk A, Ruegg T, Anderson L, Bashir T, Bernath A, Lichtenstein A, Gera J. Martin J, et al. Among authors: holmes b. J Biol Chem. 2011 May 6;286(18):16402-13. doi: 10.1074/jbc.M110.205096. Epub 2011 Mar 16. J Biol Chem. 2011. PMID: 21454539 Free PMC article.
Specific blockade of Rictor-mTOR association inhibits mTORC2 activity and is cytotoxic in glioblastoma.
Benavides-Serrato A, Lee J, Holmes B, Landon KA, Bashir T, Jung ME, Lichtenstein A, Gera J. Benavides-Serrato A, et al. Among authors: holmes b. PLoS One. 2017 Apr 28;12(4):e0176599. doi: 10.1371/journal.pone.0176599. eCollection 2017. PLoS One. 2017. Retraction in: PLoS One. 2023 Sep 8;18(9):e0291490. doi: 10.1371/journal.pone.0291490. PMID: 28453552 Free PMC article. Retracted.
712 results