Roeder RG - Search Results

1

Integrative epigenomic analysis identifies biomarkers and therapeutic targets in adult B-acute lymphoblastic leukemia.

Geng H, Brennan S, Milne TA, Chen WY, Li Y, Hurtz C, Kweon SM, Zickl L, Shojaee S, Neuberg D, Huang C, Biswas D, Xin Y, Racevskis J, Ketterling RP, Luger SM, Lazarus H, Tallman MS, Rowe JM, Litzow MR, Guzman ML, Allis CD, Roeder RG, Müschen M, Paietta E, Elemento O, Melnick AM. Geng H, et al. Among authors: roeder rg. Cancer Discov. 2012 Nov;2(11):1004-23. doi: 10.1158/2159-8290.CD-12-0208. Epub 2012 Oct 29. Cancer Discov. 2012. PMID: 23107779 Free PMC article.

2

Human PAD4 regulates histone arginine methylation levels via demethylimination.

Wang Y, Wysocka J, Sayegh J, Lee YH, Perlin JR, Leonelli L, Sonbuchner LS, McDonald CH, Cook RG, Dou Y, Roeder RG, Clarke S, Stallcup MR, Allis CD, Coonrod SA. Wang Y, et al. Among authors: roeder rg. Science. 2004 Oct 8;306(5694):279-83. doi: 10.1126/science.1101400. Epub 2004 Sep 2. Science. 2004. PMID: 15345777

3

Menin and MLL cooperatively regulate expression of cyclin-dependent kinase inhibitors.

Milne TA, Hughes CM, Lloyd R, Yang Z, Rozenblatt-Rosen O, Dou Y, Schnepp RW, Krankel C, Livolsi VA, Gibbs D, Hua X, Roeder RG, Meyerson M, Hess JL. Milne TA, et al. Among authors: roeder rg. Proc Natl Acad Sci U S A. 2005 Jan 18;102(3):749-54. doi: 10.1073/pnas.0408836102. Epub 2005 Jan 7. Proc Natl Acad Sci U S A. 2005. PMID: 15640349 Free PMC article.

4

WDR5 associates with histone H3 methylated at K4 and is essential for H3 K4 methylation and vertebrate development.

Wysocka J, Swigut T, Milne TA, Dou Y, Zhang X, Burlingame AL, Roeder RG, Brivanlou AH, Allis CD. Wysocka J, et al. Among authors: roeder rg. Cell. 2005 Jun 17;121(6):859-72. doi: 10.1016/j.cell.2005.03.036. Cell. 2005. PMID: 15960974 Free article.

5

Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF.

Dou Y, Milne TA, Tackett AJ, Smith ER, Fukuda A, Wysocka J, Allis CD, Chait BT, Hess JL, Roeder RG. Dou Y, et al. Among authors: roeder rg. Cell. 2005 Jun 17;121(6):873-85. doi: 10.1016/j.cell.2005.04.031. Cell. 2005. PMID: 15960975 Free article.

6

MLL associates specifically with a subset of transcriptionally active target genes.

Milne TA, Dou Y, Martin ME, Brock HW, Roeder RG, Hess JL. Milne TA, et al. Among authors: roeder rg. Proc Natl Acad Sci U S A. 2005 Oct 11;102(41):14765-70. doi: 10.1073/pnas.0503630102. Epub 2005 Sep 30. Proc Natl Acad Sci U S A. 2005. PMID: 16199523 Free PMC article.

7

Regulation of MLL1 H3K4 methyltransferase activity by its core components.

Dou Y, Milne TA, Ruthenburg AJ, Lee S, Lee JW, Verdine GL, Allis CD, Roeder RG. Dou Y, et al. Among authors: roeder rg. Nat Struct Mol Biol. 2006 Aug;13(8):713-9. doi: 10.1038/nsmb1128. Epub 2006 Jul 30. Nat Struct Mol Biol. 2006. PMID: 16878130

8

RAD6-Mediated transcription-coupled H2B ubiquitylation directly stimulates H3K4 methylation in human cells.

Kim J, Guermah M, McGinty RK, Lee JS, Tang Z, Milne TA, Shilatifard A, Muir TW, Roeder RG. Kim J, et al. Among authors: roeder rg. Cell. 2009 May 1;137(3):459-71. doi: 10.1016/j.cell.2009.02.027. Cell. 2009. PMID: 19410543 Free PMC article.

9

Multiple interactions recruit MLL1 and MLL1 fusion proteins to the HOXA9 locus in leukemogenesis.

Milne TA, Kim J, Wang GG, Stadler SC, Basrur V, Whitcomb SJ, Wang Z, Ruthenburg AJ, Elenitoba-Johnson KS, Roeder RG, Allis CD. Milne TA, et al. Among authors: roeder rg. Mol Cell. 2010 Jun 25;38(6):853-63. doi: 10.1016/j.molcel.2010.05.011. Epub 2010 Jun 10. Mol Cell. 2010. PMID: 20541448 Free PMC article.

10

Role for Dpy-30 in ES cell-fate specification by regulation of H3K4 methylation within bivalent domains.

Jiang H, Shukla A, Wang X, Chen WY, Bernstein BE, Roeder RG. Jiang H, et al. Among authors: roeder rg. Cell. 2011 Feb 18;144(4):513-25. doi: 10.1016/j.cell.2011.01.020. Cell. 2011. PMID: 21335234 Free PMC article.

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