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Swietemicrolides A-D, mexicanolide-type limonoids from the bark of Swietenia macrophylla with in vitro cytotoxic and alpha-glucosidase inhibitory activities.
Tran TT, Trinh DH, Trinh BTD, Bui DN, Nguyen LD, Tran PT. Tran TT, et al. RSC Adv. 2024 Jun 11;14(26):18608-18616. doi: 10.1039/d4ra01954g. eCollection 2024 Jun 6. RSC Adv. 2024. PMID: 38863811 Free PMC article.
Four new mexicanolide-type limonoids, swietemicrolides A-D (1-4), together with three known compounds (5-7) were isolated from an ethyl acetate extract of the bark of Swietenia microphylla. 1 and 2 had 1,8-hemiacetal systems whilst 3 and 4 shared hexacyclic skeletons consi …
Four new mexicanolide-type limonoids, swietemicrolides A-D (1-4), together with three known compounds (5-7) were isolated from an eth …
Passifetilactones A-E, Fatty Acid Lactones from the Fruit and Flowers of Passiflora foetida with Cytotoxic Activity.
Ponsuwan K, Nathabumroong S, Lekphrom R, Sorin S, Saengboonmee C, Senawong T, Tontapha S, Schevenels FT. Ponsuwan K, et al. J Nat Prod. 2024 May 24. doi: 10.1021/acs.jnatprod.4c00463. Online ahead of print. J Nat Prod. 2024. PMID: 38787359
Phytochemical investigation of the fruit and flowers of Passiflora foetida led to the isolation of 14 compounds, of which five are previously undescribed fatty acid lactones. Four 2-pyrones, passifetilactones A-D (1-4), and one furanone, passifetilactone E (5), were identi …
Phytochemical investigation of the fruit and flowers of Passiflora foetida led to the isolation of 14 compounds, of which five are previousl …
Efficacy and safety of telitacicept therapy in systemic lupus erythematosus with hematological involvement.
Cheng J, Peng Y, Wu Q, Wu Q, He J, Yuan G. Cheng J, et al. Clin Rheumatol. 2024 May 20. doi: 10.1007/s10067-024-06992-7. Online ahead of print. Clin Rheumatol. 2024. PMID: 38767710
We compared their demographic characteristics, clinical manifestations, and laboratory indicators before and after the administration of telitacicept. RESULTS: A total of 22 patients received telitacicept treatment for a median duration of 10.4 months (ranging from 6 to 19 …
We compared their demographic characteristics, clinical manifestations, and laboratory indicators before and after the administration …
Patumantanes A-D, seco-Polycyclic Polyprenylated Acylphloroglucinols with Diverse Carbon Skeletons from Hypericum patulum.
Duan Y, Tao B, Shi Z, Guo Y, Zhang Y, Zou Y, Qi C, Zhang Y. Duan Y, et al. J Org Chem. 2024 Jun 7;89(11):8076-8083. doi: 10.1021/acs.joc.4c00735. Epub 2024 May 20. J Org Chem. 2024. PMID: 38767586
Patumantanes A-D (1-4), four new seco-polycyclic polyprenylated acylphloroglucinols (PPAPs) were isolated from Hypericum patulum. ...
Patumantanes A-D (1-4), four new seco-polycyclic polyprenylated acylphloroglucinols (PPAPs) were isolated from Hypericum patulum. ...
A red-fleshed apple rich in anthocyanins improves endothelial function, reduces inflammation, and modulates the immune system in hypercholesterolemic subjects: the AppleCOR study.
Pedret A, Companys J, Calderón-Pérez L, Llauradó E, Pla-Pagà L, Salamanca P, Sandoval-Ramírez BA, Catalán Ú, Fernández-Castillejo S, Yuste S, Macià A, Gutiérrez-Tordera L, Bulló M, Camps J, Canela N, Valls RM, Rubió-Piqué L, Motilva MJ, Solà R. Pedret A, et al. Food Funct. 2024 Jun 4;15(11):5825-5841. doi: 10.1039/d3fo05114e. Food Funct. 2024. PMID: 38751340 Clinical Trial.
Three products reduced C1q, C4 and Factor B, and RFA and AI reduced C3. Although both RFA and AI have a similar ACN content, RFA, by a matrix effect, induced more improvements in inflammation, whereas AI improved the lipid profile. ...
Three products reduced C1q, C4 and Factor B, and RFA and AI reduced C3. Although both RFA and AI have a similar ACN content, RFA, by …
High progesterone levels on the day after HCG injection has no effect on clinical pregnancy outcomes in in vitro fertilization-embryo transfer.
Liang Z, Huang Q, Huang J, Wu J, Zeng D, Huang P. Liang Z, et al. Front Endocrinol (Lausanne). 2024 Apr 16;15:1372753. doi: 10.3389/fendo.2024.1372753. eCollection 2024. Front Endocrinol (Lausanne). 2024. PMID: 38689731 Free PMC article.

Excluding cycles with progesterone levels 1.5ng/ml on HCG injection, a total of 781 cycles were identified according to the standard, and they were divided into five groups according to the progesterone level on the day after HCG: Group A: progesterone level < 2.5 ng/ml (n = 1

…
Excluding cycles with progesterone levels 1.5ng/ml on HCG injection, a total of 781 cycles were identified according to the standard, and th …
Lemneolemnanes A-D, Four Uncommon Sesquiterpenoids from the Soft Coral Lemnalia sp.
Zong Y, Jin TY, Yang JJ, Wang KY, Shi X, Zhang Y, Li PL. Zong Y, et al. Mar Drugs. 2024 Mar 26;22(4):145. doi: 10.3390/md22040145. Mar Drugs. 2024. PMID: 38667762 Free PMC article.
Four undescribed sesquiterpenoids, lemneolemnanes A-D (1-4), have been isolated from the marine soft coral Lemnalia sp. ...Compound 3 possesses an uncommonly rearranged carbon skeleton, while 4 has a 6/5/5 tricyclic system. Compound 1 showed significant anti-Alzheimer's di …
Four undescribed sesquiterpenoids, lemneolemnanes A-D (1-4), have been isolated from the marine soft coral Lemnalia sp. ...Compound 3 …
Pembrolizumab Plus Binimetinib With or Without Chemotherapy for MSS/pMMR Metastatic Colorectal Cancer: Outcomes From KEYNOTE-651 Cohorts A, C, and E.
Chen EX, Kavan P, Tehfe M, Kortmansky JS, Sawyer MB, Chiorean EG, Lieu CH, Polite B, Wong L, Fakih M, Spencer K, Chaves J, Li C, Leconte P, Adelberg D, Kim R. Chen EX, et al. Clin Colorectal Cancer. 2024 Jun;23(2):183-193. doi: 10.1016/j.clcc.2024.03.002. Epub 2024 Apr 1. Clin Colorectal Cancer. 2024. PMID: 38653648 Clinical Trial.
Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries in 204 countries and territories and 811 subnational locations, 1990-2021: a systematic analysis for the Global Burden of Disease Study 2021.
GBD 2021 Diseases and Injuries Collaborators. GBD 2021 Diseases and Injuries Collaborators. Lancet. 2024 May 18;403(10440):2133-2161. doi: 10.1016/S0140-6736(24)00757-8. Epub 2024 Apr 17. Lancet. 2024. PMID: 38642570 Free PMC article.
801 results