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A randomized, double-blind, placebo-controlled phase II study of eculizumab in patients with refractory generalized myasthenia gravis.
Howard JF Jr, Barohn RJ, Cutter GR, Freimer M, Juel VC, Mozaffar T, Mellion ML, Benatar MG, Farrugia ME, Wang JJ, Malhotra SS, Kissel JT; MG Study Group. Howard JF Jr, et al. Among authors: malhotra ss. Muscle Nerve. 2013 Jul;48(1):76-84. doi: 10.1002/mus.23839. Epub 2013 Apr 30. Muscle Nerve. 2013. PMID: 23512355 Clinical Trial.
Strengthening primary health care through community health workers in South Asia.
Shrestha P, Afsana K, Weerasinghe MC, Perry HB, Joshi H, Rana N, Memon ZA, Khaled N, Malhotra S, Bhardwaj S, Kafle S, Inagaki Y, Schimdt A, Hodgins S, Neupane D, Rao KD. Shrestha P, et al. Among authors: malhotra s. Lancet Reg Health Southeast Asia. 2024 Aug 20;28:100463. doi: 10.1016/j.lansea.2024.100463. eCollection 2024 Sep. Lancet Reg Health Southeast Asia. 2024. PMID: 39301268 Free PMC article. Review.
Discovery of GNE-6893, a Potent, Selective, Orally Bioavailable Small Molecule Inhibitor of HPK1.
Tellis JC, Wei B, Siu M, An L, Chan GK, Chen Y, Du X, Gazzard L, Hu B, Kiefer J, Kakiuchi-Kiyota S, Lainchbury M, Linehan JL, Luo X, Malhotra S, Mendonca R, Pang J, Ran Y, Sethuraman V, Seward E, Sneeringer C, Su D, Wang W, Wu P, Moffat JG, Heffron TP, Choo EF, Chan BK. Tellis JC, et al. Among authors: malhotra s. ACS Med Chem Lett. 2024 Sep 3;15(9):1606-1614. doi: 10.1021/acsmedchemlett.4c00319. eCollection 2024 Sep 12. ACS Med Chem Lett. 2024. PMID: 39291002
Candidaemia and Central Line-Associated Candidaemia in a Network of Indian ICUs: Impact of COVID-19 Pandemic.
Mathur P, Srivastav S, Thakur AK, Parveen R, Puraswani M, Srivastava AK, Chakrabarti A, Rodrigues C, Balaji V, Ray P, Biswal M, Wattal C, Venkatesh V, Sethuraman N, Bhattacharya S, Nag VL, Tak V, Behera B, Goel N, Iravane J, Mukherjee S, Ray R, Singh SK, Mukhopadhyay C, Michael JS, Fomda BA, Chelliah J, Shetty A, Karuna T, Ningombam A, Kumar S, Soni KD, Sagar S, Aggrawal R, Gupta D, Singh GP, Bindra A, Farooque K, Purwar S, Khadanga S, Vandana KE, Varma M, Deotale V, Das P, Lohiya R, Prasad A, Gupta PK, Omar BJ, Aggarwal A, Baqal S, Devi KR, Singh LC, Chatterji S, Goel G, Mukherjee S, Ramanathan YV, Sonowal A, Verma P, Mahapatra A, Hallur V, Gaikwad UN, Bhargava A, Padmaja K, Bheerappa N, Jain V, Bhatia P, Singh K, Khera D, Gupta N, Paul H, Verma S, Arshad Z, Jhaj R, Malik S, Thirunarayan MA, Raj HJ, Gupta P, Himanshu D, Rudramurthy SM, Nath R, Gur R, Lyngdoh NM, Lyngdoh C, Devi S, Malhotra S, Gaind R, Saksena R, Sharma R, Walia K. Mathur P, et al. Among authors: malhotra s. Mycoses. 2024 Sep;67(9):e13790. doi: 10.1111/myc.13790. Mycoses. 2024. PMID: 39278818
NOTCH3 p.Arg1231Cys is markedly enriched in South Asians and associated with stroke.
Rodriguez-Flores JL, Khalid S, Parikshak N, Rasheed A, Ye B, Kapoor M, Backman J, Sepehrband F, Gioia SAD, Gelfman S, De T, Banerjee N, Sharma D, Martinez H, Castaneda S, D'Ambrosio D, Zhang XA, Xun P, Tsai E, Tsai IC; Regeneron Genetics Center; Khan MZ, Jahanzaib M, Mian MR, Liaqat MB, Mahmood K, Salam TU, Hussain M, Iqbal J, Aslam F, Cantor MN, Tzoneva G, Overton J, Marchini J, Reid JG, Baras A, Verweij N, Lotta LA, Coppola G, Karalis K, Economides A, Fazio S, Liedtke W, Danesh J, Kamal A, Frossard P, Coleman T, Shuldiner AR, Saleheen D. Rodriguez-Flores JL, et al. Nat Commun. 2024 Sep 13;15(1):8029. doi: 10.1038/s41467-024-51819-3. Nat Commun. 2024. PMID: 39271666 Free PMC article.
MiRNA-based therapeutic potential in multiple sclerosis.
Zabalza A, Pappolla A, Comabella M, Montalban X, Malhotra S. Zabalza A, et al. Among authors: malhotra s. Front Immunol. 2024 Aug 29;15:1441733. doi: 10.3389/fimmu.2024.1441733. eCollection 2024. Front Immunol. 2024. PMID: 39267760 Free PMC article. Review.
Agonist antibody to guanylate cyclase receptor NPR1 regulates vascular tone.
Dunn ME, Kithcart A, Kim JH, Ho AJ, Franklin MC, Romero Hernandez A, de Hoon J, Botermans W, Meyer J, Jin X, Zhang D, Torello J, Jasewicz D, Kamat V, Garnova E, Liu N, Rosconi M, Pan H, Karnik S, Burczynski ME, Zheng W, Rafique A, Nielsen JB, De T, Verweij N, Pandit A, Locke A, Chalasani N, Melander O, Schwantes-An TH; Penn Medicine Biobank; Baras A, Lotta LA, Musser BJ, Mastaitis J, Devalaraja-Narashimha KB, Rankin AJ, Huang T, Herman G, Olson W, Murphy AJ, Yancopoulos GD, Olenchock BA, Morton L. Dunn ME, et al. Nature. 2024 Sep;633(8030):654-661. doi: 10.1038/s41586-024-07903-1. Epub 2024 Sep 11. Nature. 2024. PMID: 39261724 Free PMC article.
2,155 results