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Myeloid cell HIF-1α regulates asthma airway resistance and eosinophil function.
Crotty Alexander LE, Akong-Moore K, Feldstein S, Johansson P, Nguyen A, McEachern EK, Nicatia S, Cowburn AS, Olson J, Cho JY, Isaacs H Jr, Johnson RS, Broide DH, Nizet V. Crotty Alexander LE, et al. Among authors: cowburn as. J Mol Med (Berl). 2013 May;91(5):637-44. doi: 10.1007/s00109-012-0986-9. Epub 2012 Dec 19. J Mol Med (Berl). 2013. PMID: 23250618 Free PMC article.
Epidermal deletion of HIF-2α stimulates wound closure.
Cowburn AS, Alexander LEC, Southwood M, Nizet V, Chilvers ER, Johnson RS. Cowburn AS, et al. J Invest Dermatol. 2014 Mar;134(3):801-808. doi: 10.1038/jid.2013.395. Epub 2013 Sep 13. J Invest Dermatol. 2014. PMID: 24037341 Free PMC article.
HIF2α-arginase axis is essential for the development of pulmonary hypertension.
Cowburn AS, Crosby A, Macias D, Branco C, Colaço RD, Southwood M, Toshner M, Crotty Alexander LE, Morrell NW, Chilvers ER, Johnson RS. Cowburn AS, et al. Proc Natl Acad Sci U S A. 2016 Aug 2;113(31):8801-6. doi: 10.1073/pnas.1602978113. Epub 2016 Jul 18. Proc Natl Acad Sci U S A. 2016. PMID: 27432976 Free PMC article.
HIF isoforms in the skin differentially regulate systemic arterial pressure.
Cowburn AS, Takeda N, Boutin AT, Kim JW, Sterling JC, Nakasaki M, Southwood M, Goldrath AW, Jamora C, Nizet V, Chilvers ER, Johnson RS. Cowburn AS, et al. Proc Natl Acad Sci U S A. 2013 Oct 22;110(43):17570-5. doi: 10.1073/pnas.1306942110. Epub 2013 Oct 7. Proc Natl Acad Sci U S A. 2013. PMID: 24101470 Free PMC article.
HIF-2α is essential for carotid body development and function.
Macias D, Cowburn AS, Torres-Torrelo H, Ortega-Sáenz P, López-Barneo J, Johnson RS. Macias D, et al. Among authors: cowburn as. Elife. 2018 Apr 19;7:e34681. doi: 10.7554/eLife.34681. Elife. 2018. PMID: 29671738 Free PMC article.
Evasion of Neutrophil Extracellular Traps by Respiratory Pathogens.
Storisteanu DM, Pocock JM, Cowburn AS, Juss JK, Nadesalingam A, Nizet V, Chilvers ER. Storisteanu DM, et al. Among authors: cowburn as. Am J Respir Cell Mol Biol. 2017 Apr;56(4):423-431. doi: 10.1165/rcmb.2016-0193PS. Am J Respir Cell Mol Biol. 2017. PMID: 27854516 Free PMC article. Review.
HIF-1α-PDK1 axis-induced active glycolysis plays an essential role in macrophage migratory capacity.
Semba H, Takeda N, Isagawa T, Sugiura Y, Honda K, Wake M, Miyazawa H, Yamaguchi Y, Miura M, Jenkins DM, Choi H, Kim JW, Asagiri M, Cowburn AS, Abe H, Soma K, Koyama K, Katoh M, Sayama K, Goda N, Johnson RS, Manabe I, Nagai R, Komuro I. Semba H, et al. Among authors: cowburn as. Nat Commun. 2016 May 18;7:11635. doi: 10.1038/ncomms11635. Nat Commun. 2016. PMID: 27189088 Free PMC article.
51 results