Slepushkin V - Search Results

1

Antiviral effects of autologous CD4 T cells genetically modified with a conditionally replicating lentiviral vector expressing long antisense to HIV.

Tebas P, Stein D, Binder-Scholl G, Mukherjee R, Brady T, Rebello T, Humeau L, Kalos M, Papasavvas E, Montaner LJ, Schullery D, Shaheen F, Brennan AL, Zheng Z, Cotte J, Slepushkin V, Veloso E, Mackley A, Hwang WT, Aberra F, Zhan J, Boyer J, Collman RG, Bushman FD, Levine BL, June CH. Tebas P, et al. Among authors: slepushkin v. Blood. 2013 Feb 28;121(9):1524-33. doi: 10.1182/blood-2012-07-447250. Epub 2012 Dec 20. Blood. 2013. PMID: 23264589 Free PMC article. Clinical Trial.

2

Gene transfer in humans using a conditionally replicating lentiviral vector.

Levine BL, Humeau LM, Boyer J, MacGregor RR, Rebello T, Lu X, Binder GK, Slepushkin V, Lemiale F, Mascola JR, Bushman FD, Dropulic B, June CH. Levine BL, et al. Among authors: slepushkin v. Proc Natl Acad Sci U S A. 2006 Nov 14;103(46):17372-7. doi: 10.1073/pnas.0608138103. Epub 2006 Nov 7. Proc Natl Acad Sci U S A. 2006. PMID: 17090675 Free PMC article.

3

Efficient lentiviral vector-mediated control of HIV-1 replication in CD4 lymphocytes from diverse HIV+ infected patients grouped according to CD4 count and viral load.

Humeau LM, Binder GK, Lu X, Slepushkin V, Merling R, Echeagaray P, Pereira M, Slepushkina T, Barnett S, Dropulic LK, Carroll R, Levine BL, June CH, Dropulic B. Humeau LM, et al. Among authors: slepushkin v. Mol Ther. 2004 Jun;9(6):902-13. doi: 10.1016/j.ymthe.2004.03.005. Mol Ther. 2004. PMID: 15194057 Free article.

4

Regulatory considerations for novel gene therapy products: a review of the process leading to the first clinical lentiviral vector.

Manilla P, Rebello T, Afable C, Lu X, Slepushkin V, Humeau LM, Schonely K, Ni Y, Binder GK, Levine BL, MacGregor RR, June CH, Dropulic B. Manilla P, et al. Among authors: slepushkin v. Hum Gene Ther. 2005 Jan;16(1):17-25. doi: 10.1089/hum.2005.16.17. Hum Gene Ther. 2005. PMID: 15703485 Review.

5

ABC transporter inhibitors that are substrates enhance lentiviral vector transduction into primitive hematopoietic progenitor cells.

Davis BM, Humeau L, Slepushkin V, Binder G, Korshalla L, Ni Y, Ogunjimi EO, Chang LF, Lu X, Dropulic B. Davis BM, et al. Among authors: slepushkin v. Blood. 2004 Jul 15;104(2):364-73. doi: 10.1182/blood-2003-07-2363. Epub 2004 Apr 1. Blood. 2004. PMID: 15059841 Free article.

6

Potent inhibition of simian immunodeficiency virus (SIV) replication by an SIV-based lentiviral vector expressing antisense Env.

Braun SE, Lu XV, Wong FE, Connole M, Qiu G, Chen Z, Slepushkina T, Slepushkin V, Humeau LM, Dropulic B, Johnson RP. Braun SE, et al. Among authors: slepushkin v. Hum Gene Ther. 2007 Jul;18(7):653-64. doi: 10.1089/hum.2007.003. Hum Gene Ther. 2007. PMID: 17600461

7

Generation of a packaging cell line for prolonged large-scale production of high-titer HIV-1-based lentiviral vector.

Ni Y, Sun S, Oparaocha I, Humeau L, Davis B, Cohen R, Binder G, Chang YN, Slepushkin V, Dropulic B. Ni Y, et al. Among authors: slepushkin v. J Gene Med. 2005 Jun;7(6):818-34. doi: 10.1002/jgm.726. J Gene Med. 2005. PMID: 15693055

8

Inhibition of simian/human immunodeficiency virus replication in CD4+ T cells derived from lentiviral-transduced CD34+ hematopoietic cells.

Braun SE, Wong FE, Connole M, Qiu G, Lee L, Gillis J, Lu X, Humeau L, Slepushkin V, Binder GK, Dropulic B, Johnson RP. Braun SE, et al. Among authors: slepushkin v. Mol Ther. 2005 Dec;12(6):1157-67. doi: 10.1016/j.ymthe.2005.07.698. Epub 2005 Sep 15. Mol Ther. 2005. PMID: 16168713 Free article.

9

Safe two-plasmid production for the first clinical lentivirus vector that achieves >99% transduction in primary cells using a one-step protocol.

Lu X, Humeau L, Slepushkin V, Binder G, Yu Q, Slepushkina T, Chen Z, Merling R, Davis B, Chang YN, Dropulic B. Lu X, et al. Among authors: slepushkin v. J Gene Med. 2004 Sep;6(9):963-73. doi: 10.1002/jgm.593. J Gene Med. 2004. PMID: 15352069

10

Infection of human airway epithelia with H1N1, H2N2, and H3N2 influenza A virus strains.

Slepushkin VA, Staber PD, Wang G, McCray PB Jr, Davidson BL. Slepushkin VA, et al. Mol Ther. 2001 Mar;3(3):395-402. doi: 10.1006/mthe.2001.0277. Mol Ther. 2001. PMID: 11273782 Free PMC article.

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