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Sphingosine-1-phosphate links persistent STAT3 activation, chronic intestinal inflammation, and development of colitis-associated cancer.
Liang J, Nagahashi M, Kim EY, Harikumar KB, Yamada A, Huang WC, Hait NC, Allegood JC, Price MM, Avni D, Takabe K, Kordula T, Milstien S, Spiegel S. Liang J, et al. Among authors: avni d. Cancer Cell. 2013 Jan 14;23(1):107-20. doi: 10.1016/j.ccr.2012.11.013. Epub 2012 Dec 27. Cancer Cell. 2013. PMID: 23273921 Free PMC article.
Sphingosine-1-phosphate in chronic intestinal inflammation and cancer.
Nagahashi M, Hait NC, Maceyka M, Avni D, Takabe K, Milstien S, Spiegel S. Nagahashi M, et al. Among authors: avni d. Adv Biol Regul. 2014 Jan;54:112-20. doi: 10.1016/j.jbior.2013.10.001. Epub 2013 Oct 16. Adv Biol Regul. 2014. PMID: 24210073 Free PMC article. Review.
Sphingosine-1-phosphate phosphatase 2 promotes disruption of mucosal integrity, and contributes to ulcerative colitis in mice and humans.
Huang WC, Liang J, Nagahashi M, Avni D, Yamada A, Maceyka M, Wolen AR, Kordula T, Milstien S, Takabe K, Oravecz T, Spiegel S. Huang WC, et al. Among authors: avni d. FASEB J. 2016 Aug;30(8):2945-58. doi: 10.1096/fj.201600394R. Epub 2016 Apr 29. FASEB J. 2016. PMID: 27130484 Free PMC article.
SGPP2 may represent a novel therapeutic target in inflammatory bowel disease.-Huang, W.-C., Liang, J., Nagahashi, M., Avni, D., Yamada, A., Maceyka, M., Wolen, A. R., Kordula, T., Milstien, S., Takabe, K., Oravecz, T., Spiegel, S. ...
SGPP2 may represent a novel therapeutic target in inflammatory bowel disease.-Huang, W.-C., Liang, J., Nagahashi, M., Avni, D. …
Aberrant ORM (yeast)-like protein isoform 3 (ORMDL3) expression dysregulates ceramide homeostasis in cells and ceramide exacerbates allergic asthma in mice.
Oyeniran C, Sturgill JL, Hait NC, Huang WC, Avni D, Maceyka M, Newton J, Allegood JC, Montpetit A, Conrad DH, Milstien S, Spiegel S. Oyeniran C, et al. Among authors: avni d. J Allergy Clin Immunol. 2015 Oct;136(4):1035-46.e6. doi: 10.1016/j.jaci.2015.02.031. Epub 2015 Apr 2. J Allergy Clin Immunol. 2015. PMID: 25842287 Free PMC article.
Hepatic apolipoprotein M (apoM) overexpression stimulates formation of larger apoM/sphingosine 1-phosphate-enriched plasma high density lipoprotein.
Liu M, Seo J, Allegood J, Bi X, Zhu X, Boudyguina E, Gebre AK, Avni D, Shah D, Sorci-Thomas MG, Thomas MJ, Shelness GS, Spiegel S, Parks JS. Liu M, et al. Among authors: avni d. J Biol Chem. 2014 Jan 31;289(5):2801-14. doi: 10.1074/jbc.M113.499913. Epub 2013 Dec 6. J Biol Chem. 2014. PMID: 24318881 Free PMC article.
63 results