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Microglia emerge from erythromyeloid precursors via Pu.1- and Irf8-dependent pathways.
Kierdorf K, Erny D, Goldmann T, Sander V, Schulz C, Perdiguero EG, Wieghofer P, Heinrich A, Riemke P, Hölscher C, Müller DN, Luckow B, Brocker T, Debowski K, Fritz G, Opdenakker G, Diefenbach A, Biber K, Heikenwalder M, Geissmann F, Rosenbauer F, Prinz M. Kierdorf K, et al. Among authors: geissmann f. Nat Neurosci. 2013 Mar;16(3):273-80. doi: 10.1038/nn.3318. Epub 2013 Jan 20. Nat Neurosci. 2013. PMID: 23334579
A lineage of myeloid cells independent of Myb and hematopoietic stem cells.
Schulz C, Gomez Perdiguero E, Chorro L, Szabo-Rogers H, Cagnard N, Kierdorf K, Prinz M, Wu B, Jacobsen SE, Pollard JW, Frampton J, Liu KJ, Geissmann F. Schulz C, et al. Among authors: geissmann f. Science. 2012 Apr 6;336(6077):86-90. doi: 10.1126/science.1219179. Epub 2012 Mar 22. Science. 2012. PMID: 22442384
Tissue-resident macrophages originate from yolk-sac-derived erythro-myeloid progenitors.
Gomez Perdiguero E, Klapproth K, Schulz C, Busch K, Azzoni E, Crozet L, Garner H, Trouillet C, de Bruijn MF, Geissmann F, Rodewald HR. Gomez Perdiguero E, et al. Among authors: geissmann f. Nature. 2015 Feb 26;518(7540):547-51. doi: 10.1038/nature13989. Epub 2014 Dec 3. Nature. 2015. PMID: 25470051 Free PMC article.
The development and maintenance of resident macrophages.
Perdiguero EG, Geissmann F. Perdiguero EG, et al. Among authors: geissmann f. Nat Immunol. 2016 Jan;17(1):2-8. doi: 10.1038/ni.3341. Nat Immunol. 2016. PMID: 26681456 Free PMC article. Review.
Development and function of tissue resident macrophages in mice.
Kierdorf K, Prinz M, Geissmann F, Gomez Perdiguero E. Kierdorf K, et al. Among authors: geissmann f. Semin Immunol. 2015 Dec;27(6):369-78. doi: 10.1016/j.smim.2016.03.017. Epub 2016 Mar 29. Semin Immunol. 2015. PMID: 27036090 Free PMC article. Review.
Origin, fate and dynamics of macrophages at central nervous system interfaces.
Goldmann T, Wieghofer P, Jordão MJ, Prutek F, Hagemeyer N, Frenzel K, Amann L, Staszewski O, Kierdorf K, Krueger M, Locatelli G, Hochgerner H, Zeiser R, Epelman S, Geissmann F, Priller J, Rossi FM, Bechmann I, Kerschensteiner M, Linnarsson S, Jung S, Prinz M. Goldmann T, et al. Among authors: geissmann f. Nat Immunol. 2016 Jul;17(7):797-805. doi: 10.1038/ni.3423. Epub 2016 May 2. Nat Immunol. 2016. PMID: 27135602 Free PMC article.
A somatic mutation in erythro-myeloid progenitors causes neurodegenerative disease.
Mass E, Jacome-Galarza CE, Blank T, Lazarov T, Durham BH, Ozkaya N, Pastore A, Schwabenland M, Chung YR, Rosenblum MK, Prinz M, Abdel-Wahab O, Geissmann F. Mass E, et al. Among authors: geissmann f. Nature. 2017 Sep 21;549(7672):389-393. doi: 10.1038/nature23672. Epub 2017 Aug 30. Nature. 2017. PMID: 28854169 Free PMC article.
144 results