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431 results

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Page 1
Pharmacological properties and predicted binding mode of arylmethylene quinuclidine-like derivatives at the α3β4 nicotinic acetylcholine receptor (nAChR).
Kombo DC, Hauser TA, Grinevich VP, Melvin MS, Strachan JP, Sidach SS, Chewning J, Fedorov N, Tallapragada K, Breining SR, Miller CH. Kombo DC, et al. Among authors: miller ch. Bioorg Med Chem Lett. 2013 Mar 1;23(5):1450-5. doi: 10.1016/j.bmcl.2012.12.054. Epub 2012 Dec 28. Bioorg Med Chem Lett. 2013. PMID: 23352509
Synthesis of 2-(pyridin-3-yl)-1-azabicyclo[3.2.2]nonane, 2-(pyridin-3-yl)-1-azabicyclo[2.2.2]octane, and 2-(pyridin-3-yl)-1-azabicyclo[3.2.1]octane, a class of potent nicotinic acetylcholine receptor-ligands.
Bhatti BS, Strachan JP, Breining SR, Miller CH, Tahiri P, Crooks PA, Deo N, Day CS, Caldwell WS. Bhatti BS, et al. Among authors: miller ch. J Org Chem. 2008 May 2;73(9):3497-507. doi: 10.1021/jo800028q. Epub 2008 Mar 26. J Org Chem. 2008. PMID: 18363376
Discovery of 3-(5-chloro-2-furoyl)-3,7-diazabicyclo[3.3.0]octane (TC-6683, AZD1446), a novel highly selective α4β2 nicotinic acetylcholine receptor agonist for the treatment of cognitive disorders.
Mazurov AA, Miao L, Bhatti BS, Strachan JP, Akireddy S, Murthy S, Kombo D, Xiao YD, Hammond P, Zhang J, Hauser TA, Jordan KG, Miller CH, Speake JD, Gatto GJ, Yohannes D. Mazurov AA, et al. Among authors: miller ch. J Med Chem. 2012 Nov 8;55(21):9181-94. doi: 10.1021/jm3006542. Epub 2012 Jul 27. J Med Chem. 2012. PMID: 22793665
Discovery of (2S,3R)-N-[2-(pyridin-3-ylmethyl)-1-azabicyclo[2.2.2]oct-3-yl]benzo[b]furan-2-carboxamide (TC-5619), a selective α7 nicotinic acetylcholine receptor agonist, for the treatment of cognitive disorders.
Mazurov AA, Kombo DC, Hauser TA, Miao L, Dull G, Genus JF, Fedorov NB, Benson L, Sidach S, Xiao Y, Hammond PS, James JW, Miller CH, Yohannes D. Mazurov AA, et al. Among authors: miller ch. J Med Chem. 2012 Nov 26;55(22):9793-809. doi: 10.1021/jm301048a. Epub 2012 Nov 13. J Med Chem. 2012. PMID: 23126648
Synthesis of bicyclic tertiary alpha-amino acids.
Strachan JP, Whitaker RC, Miller CH, Bhatti BS. Strachan JP, et al. Among authors: miller ch. J Org Chem. 2006 Dec 22;71(26):9909-11. doi: 10.1021/jo061977a. J Org Chem. 2006. PMID: 17168622
Publisher Correction: Female behavior drives the formation of distinct social structures in C57BL/6J versus wild-derived outbred mice in field enclosures.
Vogt CC, Zipple MN, Sprockett DD, Miller CH, Hardy SX, Arthur MK, Greenstein AM, Colvin MS, Michel LM, Moeller AH, Sheehan MJ. Vogt CC, et al. Among authors: miller ch. BMC Biol. 2024 Apr 1;22(1):72. doi: 10.1186/s12915-024-01871-8. BMC Biol. 2024. PMID: 38561721 Free PMC article. No abstract available.
431 results