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Oral administration of an adenovirus vector encoding both an avian influenza A hemagglutinin and a TLR3 ligand induces antigen specific granzyme B and IFN-γ T cell responses in humans.
Vaccine. 2013 Mar 25;31(13):1752-8. doi: 10.1016/j.vaccine.2013.01.023. Epub 2013 Jan 25.
Vaccine. 2013.
PMID: 23357198
Clinical Trial.
An adenovirus-based vaccine with a double-stranded RNA adjuvant protects mice and ferrets against H5N1 avian influenza in oral delivery models.
Scallan CD, Tingley DW, Lindbloom JD, Toomey JS, Tucker SN.
Scallan CD, et al. Among authors: tingley dw.
Clin Vaccine Immunol. 2013 Jan;20(1):85-94. doi: 10.1128/CVI.00552-12. Epub 2012 Nov 14.
Clin Vaccine Immunol. 2013.
PMID: 23155123
Free PMC article.
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Oral adenoviral-based vaccines: historical perspective and future opportunity.
Tucker SN, Tingley DW, Scallan CD.
Tucker SN, et al. Among authors: tingley dw.
Expert Rev Vaccines. 2008 Feb;7(1):25-31. doi: 10.1586/14760584.7.1.25.
Expert Rev Vaccines. 2008.
PMID: 18251691
Review.
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