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Magic angle spinning nuclear magnetic resonance spectroscopy of G protein-coupled receptors.
Methods Enzymol. 2013;522:365-89. doi: 10.1016/B978-0-12-407865-9.00017-0.
Methods Enzymol. 2013.
PMID: 23374193
Highly conserved tyrosine stabilizes the active state of rhodopsin.
Goncalves JA, South K, Ahuja S, Zaitseva E, Opefi CA, Eilers M, Vogel R, Reeves PJ, Smith SO.
Goncalves JA, et al. Among authors: opefi ca.
Proc Natl Acad Sci U S A. 2010 Nov 16;107(46):19861-6. doi: 10.1073/pnas.1009405107. Epub 2010 Nov 1.
Proc Natl Acad Sci U S A. 2010.
PMID: 21041664
Free PMC article.
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Construction of stable mammalian cell lines for inducible expression of G protein-coupled receptors.
Opefi CA, Tranter D, Smith SO, Reeves PJ.
Opefi CA, et al.
Methods Enzymol. 2015;556:283-305. doi: 10.1016/bs.mie.2014.12.020. Epub 2015 Mar 20.
Methods Enzymol. 2015.
PMID: 25857787
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Retinitis pigmentosa mutants provide insight into the role of the N-terminal cap in rhodopsin folding, structure, and function.
Opefi CA, South K, Reynolds CA, Smith SO, Reeves PJ.
Opefi CA, et al.
J Biol Chem. 2013 Nov 22;288(47):33912-33926. doi: 10.1074/jbc.M113.483032. Epub 2013 Oct 8.
J Biol Chem. 2013.
PMID: 24106275
Free PMC article.
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Free backbone carbonyls mediate rhodopsin activation.
Kimata N, Pope A, Sanchez-Reyes OB, Eilers M, Opefi CA, Ziliox M, Reeves PJ, Smith SO.
Kimata N, et al. Among authors: opefi ca.
Nat Struct Mol Biol. 2016 Aug;23(8):738-43. doi: 10.1038/nsmb.3257. Epub 2016 Jul 4.
Nat Struct Mol Biol. 2016.
PMID: 27376589
Free PMC article.
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Retinal orientation and interactions in rhodopsin reveal a two-stage trigger mechanism for activation.
Kimata N, Pope A, Eilers M, Opefi CA, Ziliox M, Hirshfeld A, Zaitseva E, Vogel R, Sheves M, Reeves PJ, Smith SO.
Kimata N, et al. Among authors: opefi ca.
Nat Commun. 2016 Sep 2;7:12683. doi: 10.1038/ncomms12683.
Nat Commun. 2016.
PMID: 27585742
Free PMC article.
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Rescue of mutant rhodopsin traffic by metformin-induced AMPK activation accelerates photoreceptor degeneration.
Athanasiou D, Aguila M, Opefi CA, South K, Bellingham J, Bevilacqua D, Munro PM, Kanuga N, Mackenzie FE, Dubis AM, Georgiadis A, Graca AB, Pearson RA, Ali RR, Sakami S, Palczewski K, Sherman MY, Reeves PJ, Cheetham ME.
Athanasiou D, et al. Among authors: opefi ca.
Hum Mol Genet. 2017 Jan 15;26(2):305-319. doi: 10.1093/hmg/ddw387.
Hum Mol Genet. 2017.
PMID: 28065882
Free PMC article.
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