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Semi-synthesis and biological evaluation of 1,2,3-triazole-based podophyllotoxin congeners as potent antitumor agents inducing apoptosis in HepG2 cells.
Chen J, Ma L, Zhang R, Tang J, Lai H, Wang J, Wang G, Xu Q, Chen T, Peng F, Qiu J, Liang X, Cao D, Ran Y, Peng A, Wei Y, Chen L. Chen J, et al. Among authors: zhang r. Arch Pharm (Weinheim). 2012 Dec;345(12):945-56. doi: 10.1002/ardp.201100438. Epub 2012 Sep 5. Arch Pharm (Weinheim). 2012. PMID: 22949330
Millepachine, a novel chalcone, induces G2/M arrest by inhibiting CDK1 activity and causing apoptosis via ROS-mitochondrial apoptotic pathway in human hepatocarcinoma cells in vitro and in vivo.
Wu W, Ye H, Wan L, Han X, Wang G, Hu J, Tang M, Duan X, Fan Y, He S, Huang L, Pei H, Wang X, Li X, Xie C, Zhang R, Yuan Z, Mao Y, Wei Y, Chen L. Wu W, et al. Among authors: zhang r. Carcinogenesis. 2013 Jul;34(7):1636-43. doi: 10.1093/carcin/bgt087. Epub 2013 Mar 7. Carcinogenesis. 2013. PMID: 23471882
Prodrugs of triterpenoids and their derivatives.
Zhou M, Zhang RH, Wang M, Xu GB, Liao SG. Zhou M, et al. Eur J Med Chem. 2017 May 5;131:222-236. doi: 10.1016/j.ejmech.2017.03.005. Epub 2017 Mar 6. Eur J Med Chem. 2017. PMID: 28329729 Review.
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