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Acyl-CoA synthetase 1 is induced by Gram-negative bacteria and lipopolysaccharide and is required for phospholipid turnover in stimulated macrophages.
Rubinow KB, Wall VZ, Nelson J, Mar D, Bomsztyk K, Askari B, Lai MA, Smith KD, Han MS, Vivekanandan-Giri A, Pennathur S, Albert CJ, Ford DA, Davis RJ, Bornfeldt KE. Rubinow KB, et al. Among authors: askari b. J Biol Chem. 2013 Apr 5;288(14):9957-9970. doi: 10.1074/jbc.M113.458372. Epub 2013 Feb 20. J Biol Chem. 2013. PMID: 23426369 Free PMC article.
Rosiglitazone inhibits acyl-CoA synthetase activity and fatty acid partitioning to diacylglycerol and triacylglycerol via a peroxisome proliferator-activated receptor-gamma-independent mechanism in human arterial smooth muscle cells and macrophages.
Askari B, Kanter JE, Sherrid AM, Golej DL, Bender AT, Liu J, Hsueh WA, Beavo JA, Coleman RA, Bornfeldt KE. Askari B, et al. Diabetes. 2007 Apr;56(4):1143-52. doi: 10.2337/db06-0267. Epub 2007 Jan 26. Diabetes. 2007. PMID: 17259370 Free PMC article.
Aggressive very low-density lipoprotein (VLDL) and LDL lowering by gene transfer of the VLDL receptor combined with a low-fat diet regimen induces regression and reduces macrophage content in advanced atherosclerotic lesions in LDL receptor-deficient mice.
MacDougall ED, Kramer F, Polinsky P, Barnhart S, Askari B, Johansson F, Varon R, Rosenfeld ME, Oka K, Chan L, Schwartz SM, Bornfeldt KE. MacDougall ED, et al. Among authors: askari b. Am J Pathol. 2006 Jun;168(6):2064-73. doi: 10.2353/ajpath.2006.051009. Am J Pathol. 2006. PMID: 16723719 Free PMC article.
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