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A novel murine model for arrhythmogenic cardiomyopathy points to a pathogenic role of Wnt signalling and miRNA dysregulation.
Calore M, Lorenzon A, Vitiello L, Poloni G, Khan MAF, Beffagna G, Dazzo E, Sacchetto C, Polishchuk R, Sabatelli P, Doliana R, Carnevale D, Lembo G, Bonaldo P, De Windt L, Braghetta P, Rampazzo A. Calore M, et al. Among authors: polishchuk r. Cardiovasc Res. 2019 Mar 15;115(4):739-751. doi: 10.1093/cvr/cvy253. Cardiovasc Res. 2019. PMID: 30304392
Akap1 Deficiency Promotes Mitochondrial Aberrations and Exacerbates Cardiac Injury Following Permanent Coronary Ligation via Enhanced Mitophagy and Apoptosis.
Schiattarella GG, Cattaneo F, Pironti G, Magliulo F, Carotenuto G, Pirozzi M, Polishchuk R, Borzacchiello D, Paolillo R, Oliveti M, Boccella N, Avvedimento M, Sepe M, Lombardi A, Busiello RA, Trimarco B, Esposito G, Feliciello A, Perrino C. Schiattarella GG, et al. Among authors: polishchuk r. PLoS One. 2016 May 2;11(5):e0154076. doi: 10.1371/journal.pone.0154076. eCollection 2016. PLoS One. 2016. PMID: 27136357 Free PMC article.
Gene transfer of master autophagy regulator TFEB results in clearance of toxic protein and correction of hepatic disease in alpha-1-anti-trypsin deficiency.
Pastore N, Blomenkamp K, Annunziata F, Piccolo P, Mithbaokar P, Maria Sepe R, Vetrini F, Palmer D, Ng P, Polishchuk E, Iacobacci S, Polishchuk R, Teckman J, Ballabio A, Brunetti-Pierri N. Pastore N, et al. Among authors: polishchuk r, polishchuk e. EMBO Mol Med. 2013 Mar;5(3):397-412. doi: 10.1002/emmm.201202046. Epub 2013 Feb 4. EMBO Mol Med. 2013. PMID: 23381957 Free PMC article.
Correction: Akap1 Deficiency Promotes Mitochondrial Aberrations and Exacerbates Cardiac Injury Following Permanent Coronary Ligation via Enhanced Mitophagy and Apoptosis.
Schiattarella GG, Cattaneo F, Pironti G, Magliulo F, Carotenuto G, Pirozzi M, Polishchuk R, Borzacchiello D, Paolillo R, Oliveti M, Boccella N, Avvedimento M, Sepe M, Gargiulo G, Lombardi A, Busiello RA, Trimarco B, Esposito G, Feliciello A, Perrino C. Schiattarella GG, et al. Among authors: polishchuk r. PLoS One. 2016 Jul 6;11(7):e0158934. doi: 10.1371/journal.pone.0158934. eCollection 2016. PLoS One. 2016. PMID: 27384315 Free PMC article.
Myopalladin knockout mice develop cardiac dilation and show a maladaptive response to mechanical pressure overload.
Filomena MC, Yamamoto DL, Carullo P, Medvedev R, Ghisleni A, Piroddi N, Scellini B, Crispino R, D'Autilia F, Zhang J, Felicetta A, Nemska S, Serio S, Tesi C, Catalucci D, Linke WA, Polishchuk R, Poggesi C, Gautel M, Bang ML. Filomena MC, et al. Among authors: polishchuk r. Elife. 2021 Sep 24;10:e58313. doi: 10.7554/eLife.58313. Elife. 2021. PMID: 34558411 Free PMC article.
169 results