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A C-terminal PDZ domain-binding sequence is required for striatal distribution of the dopamine transporter.
Rickhag M, Hansen FH, Sørensen G, Strandfelt KN, Andresen B, Gotfryd K, Madsen KL, Vestergaard-Klewe I, Ammendrup-Johnsen I, Eriksen J, Newman AH, Füchtbauer EM, Gomeza J, Woldbye DP, Wörtwein G, Gether U. Rickhag M, et al. Among authors: wortwein g. Nat Commun. 2013;4:1580. doi: 10.1038/ncomms2568. Nat Commun. 2013. PMID: 23481388 Free PMC article.
Disruption of the PDZ domain-binding motif of the dopamine transporter uniquely alters nanoscale distribution, dopamine homeostasis, and reward motivation.
Sørensen G, Rickhag M, Leo D, Lycas MD, Ridderstrøm PH, Weikop P, Lilja JH, Rifes P, Herborg F, Woldbye D, Wörtwein G, Gainetdinov RR, Fink-Jensen A, Gether U. Sørensen G, et al. Among authors: wortwein g. J Biol Chem. 2021 Dec;297(6):101361. doi: 10.1016/j.jbc.2021.101361. Epub 2021 Oct 29. J Biol Chem. 2021. PMID: 34756883 Free PMC article.
Membrane-permeable C-terminal dopamine transporter peptides attenuate amphetamine-evoked dopamine release.
Rickhag M, Owens WA, Winkler MT, Strandfelt KN, Rathje M, Sørensen G, Andresen B, Madsen KL, Jørgensen TN, Wörtwein G, Woldbye DPD, Sitte H, Daws LC, Gether U. Rickhag M, et al. Among authors: wortwein g. J Biol Chem. 2013 Sep 20;288(38):27534-27544. doi: 10.1074/jbc.M112.441295. Epub 2013 Jul 24. J Biol Chem. 2013. PMID: 23884410 Free PMC article.
Locomotor- and Reward-Enhancing Effects of Cocaine Are Differentially Regulated by Chemogenetic Stimulation of Gi-Signaling in Dopaminergic Neurons.
Runegaard AH, Sørensen AT, Fitzpatrick CM, Jørgensen SH, Petersen AV, Hansen NW, Weikop P, Andreasen JT, Mikkelsen JD, Perrier JF, Woldbye D, Rickhag M, Wortwein G, Gether U. Runegaard AH, et al. Among authors: wortwein g. eNeuro. 2018 Jun 18;5(3):ENEURO.0345-17.2018. doi: 10.1523/ENEURO.0345-17.2018. eCollection 2018 May-Jun. eNeuro. 2018. PMID: 29938215 Free PMC article.
PICK1-Deficient Mice Exhibit Impaired Response to Cocaine and Dysregulated Dopamine Homeostasis.
Jensen KL, Sørensen G, Dencker D, Owens WA, Rahbek-Clemmensen T, Brett Lever M, Runegaard AH, Riis Christensen N, Weikop P, Wörtwein G, Fink-Jensen A, Madsen KL, Daws L, Gether U, Rickhag M. Jensen KL, et al. Among authors: wortwein g. eNeuro. 2018 Jun 11;5(3):ENEURO.0422-17.2018. doi: 10.1523/ENEURO.0422-17.2018. eCollection 2018 May-Jun. eNeuro. 2018. PMID: 29911172 Free PMC article.
Neuropeptide Y Y5 receptor antagonism attenuates cocaine-induced effects in mice.
Sørensen G, Jensen M, Weikop P, Dencker D, Christiansen SH, Loland CJ, Bengtsen CH, Petersen JH, Fink-Jensen A, Wörtwein G, Woldbye DP. Sørensen G, et al. Among authors: wortwein g. Psychopharmacology (Berl). 2012 Aug;222(4):565-77. doi: 10.1007/s00213-012-2651-y. Epub 2012 Feb 25. Psychopharmacology (Berl). 2012. PMID: 22367168
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