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mTOR (Mechanistic Target of Rapamycin) Inhibition Decreases Mechanosignaling, Collagen Accumulation, and Stiffening of the Thoracic Aorta in Elastin-Deficient Mice.
Jiao Y, Li G, Li Q, Ali R, Qin L, Li W, Qyang Y, Greif DM, Geirsson A, Humphrey JD, Tellides G. Jiao Y, et al. Among authors: ali r. Arterioscler Thromb Vasc Biol. 2017 Sep;37(9):1657-1666. doi: 10.1161/ATVBAHA.117.309653. Epub 2017 Jul 27. Arterioscler Thromb Vasc Biol. 2017. PMID: 28751568 Free PMC article.
IFN-gamma primes intact human coronary arteries and cultured coronary smooth muscle cells to double-stranded RNA- and self-RNA-induced inflammatory responses by upregulating TLR3 and melanoma differentiation-associated gene 5.
Ahmad U, Ali R, Lebastchi AH, Qin L, Lo SF, Yakimov AO, Khan SF, Choy JC, Geirsson A, Pober JS, Tellides G. Ahmad U, et al. Among authors: ali r. J Immunol. 2010 Jul 15;185(2):1283-94. doi: 10.4049/jimmunol.0902283. Epub 2010 Jun 18. J Immunol. 2010. PMID: 20562257 Free PMC article.
Tgfbr2 disruption in postnatal smooth muscle impairs aortic wall homeostasis.
Li W, Li Q, Jiao Y, Qin L, Ali R, Zhou J, Ferruzzi J, Kim RW, Geirsson A, Dietz HC, Offermanns S, Humphrey JD, Tellides G. Li W, et al. Among authors: ali r. J Clin Invest. 2014 Feb;124(2):755-67. doi: 10.1172/JCI69942. Epub 2014 Jan 9. J Clin Invest. 2014. PMID: 24401272 Free PMC article.
Circulating interferon-γ-inducible Cys-X-Cys chemokine receptor 3 ligands are elevated in humans with aortic aneurysms and Cys-X-Cys chemokine receptor 3 is necessary for aneurysm formation in mice.
Gallo A, Saad A, Ali R, Dardik A, Tellides G, Geirsson A. Gallo A, et al. Among authors: ali r. J Thorac Cardiovasc Surg. 2012 Mar;143(3):704-10. doi: 10.1016/j.jtcvs.2011.08.036. Epub 2011 Sep 29. J Thorac Cardiovasc Surg. 2012. PMID: 21962843 Free PMC article.
3,076 results