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Cyclin-dependent kinase 5 activates guanine nucleotide exchange factor GIV/Girdin to orchestrate migration-proliferation dichotomy.
Bhandari D, Lopez-Sanchez I, To A, Lo IC, Aznar N, Leyme A, Gupta V, Niesman I, Maddox AL, Garcia-Marcos M, Farquhar MG, Ghosh P. Bhandari D, et al. Among authors: aznar n. Proc Natl Acad Sci U S A. 2015 Sep 1;112(35):E4874-83. doi: 10.1073/pnas.1514157112. Epub 2015 Aug 18. Proc Natl Acad Sci U S A. 2015. PMID: 26286990 Free PMC article.
Prognostic impact of total and tyrosine phosphorylated GIV/Girdin in breast cancers.
Dunkel Y, Diao K, Aznar N, Swanson L, Liu L, Zhu W, Mi XY, Ghosh P. Dunkel Y, et al. Among authors: aznar n. FASEB J. 2016 Nov;30(11):3702-3713. doi: 10.1096/fj.201600500. Epub 2016 Jul 20. FASEB J. 2016. PMID: 27440794 Free PMC article.
Further studies on larger cohorts are essential to rigorously assess the effectiveness and robustness of this algorithm in prognosticating outcome among patients with breast cancer.-Dunkel, Y., Diao, K., Aznar, N., Swanson, L., Liu, L., Zhu, W., Mi, X.-Y., Ghosh, P. …
Further studies on larger cohorts are essential to rigorously assess the effectiveness and robustness of this algorithm in prognosticating o …
Mitochondrial BMI1 maintains bioenergetic homeostasis in cells.
Banerjee Mustafi S, Aznar N, Dwivedi SK, Chakraborty PK, Basak R, Mukherjee P, Ghosh P, Bhattacharya R. Banerjee Mustafi S, et al. Among authors: aznar n. FASEB J. 2016 Dec;30(12):4042-4055. doi: 10.1096/fj.201600321R. Epub 2016 Sep 9. FASEB J. 2016. PMID: 27613804 Free PMC article.
These findings not only establish a novel extranuclear role of BMI1 in the regulation of mitochondrial bioenergetics, but also provide new mechanistic insights into the role of this proto-oncogene in stem cell differentiation, neuronal aging, and cancer.-Banerjee Mustafi, S., …
These findings not only establish a novel extranuclear role of BMI1 in the regulation of mitochondrial bioenergetics, but also provide new m …
33 results