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Page 1
Contribution of IKBKE and IFIH1 gene variants to SLE susceptibility.
Wang C, Ahlford A, Laxman N, Nordmark G, Eloranta ML, Gunnarsson I, Svenungsson E, Padyukov L, Sturfelt G, Jönsen A, Bengtsson AA, Truedsson L, Rantapää-Dahlqvist S, Sjöwall C, Sandling JK, Rönnblom L, Syvänen AC. Wang C, et al. Among authors: sturfelt g. Genes Immun. 2013 Jun;14(4):217-22. doi: 10.1038/gene.2013.9. Epub 2013 Mar 28. Genes Immun. 2013. PMID: 23535865
A candidate gene study of the type I interferon pathway implicates IKBKE and IL8 as risk loci for SLE.
Sandling JK, Garnier S, Sigurdsson S, Wang C, Nordmark G, Gunnarsson I, Svenungsson E, Padyukov L, Sturfelt G, Jönsen A, Bengtsson AA, Truedsson L, Eriksson C, Rantapää-Dahlqvist S, Mälarstig A, Strawbridge RJ, Hamsten A, Criswell LA, Graham RR, Behrens TW, Eloranta ML, Alm G, Rönnblom L, Syvänen AC. Sandling JK, et al. Among authors: sturfelt g. Eur J Hum Genet. 2011 Apr;19(4):479-84. doi: 10.1038/ejhg.2010.197. Epub 2010 Dec 22. Eur J Hum Genet. 2011. PMID: 21179067 Free PMC article.
Genes identified in Asian SLE GWASs are also associated with SLE in Caucasian populations.
Wang C, Ahlford A, Järvinen TM, Nordmark G, Eloranta ML, Gunnarsson I, Svenungsson E, Padyukov L, Sturfelt G, Jönsen A, Bengtsson AA, Truedsson L, Eriksson C, Rantapää-Dahlqvist S, Sjöwall C, Julkunen H, Criswell LA, Graham RR, Behrens TW, Kere J, Rönnblom L, Syvänen AC, Sandling JK. Wang C, et al. Among authors: sturfelt g. Eur J Hum Genet. 2013 Sep;21(9):994-9. doi: 10.1038/ejhg.2012.277. Epub 2012 Dec 19. Eur J Hum Genet. 2013. PMID: 23249952 Free PMC article.
Association analysis with microsatellite and SNP markers does not support the involvement of BCL-2 in systemic lupus erythematosus in Mexican and Swedish patients and their families.
Johansson C, Castillejo-López C, Johanneson B, Svenungsson E, Gunnarsson I, Frostegård J, Sturfelt G, Truedsson L, Löfström B, Alcocer-Varela J, Lundberg I, Gyllensten UB, Alarcón-Segovia D, Alarcón-Riquelme ME. Johansson C, et al. Among authors: sturfelt g. Genes Immun. 2000 Aug;1(6):380-5. doi: 10.1038/sj.gene.6363688. Genes Immun. 2000. PMID: 11196685
No evidence of association between genetic variants of the PDCD1 ligands and SLE.
Abelson AK, Johansson CM, Kozyrev SV, Kristjansdottir H, Gunnarsson I, Svenungsson E, Jönsen A, Lima G, Scherbarth HR, Gamron S, Allievi A, Palatnik SA, Alvarellos A, Paira S, Graf C, Guillerón C, Catoggio LJ, Prigione C, Battagliotti CG, Berbotto GA, García MA, Perandones CE, Truedsson L, Steinsson K, Sturfelt G, Pons-Estel B; Argentinean Collaborative Group; Alarcón-Riquelme ME. Abelson AK, et al. Among authors: sturfelt g. Genes Immun. 2007 Jan;8(1):69-74. doi: 10.1038/sj.gene.6364360. Epub 2006 Nov 30. Genes Immun. 2007. PMID: 17136123
Analysis of HLA DR, HLA DQ, C4A, FcgammaRIIa, FcgammaRIIIa, MBL, and IL-1Ra allelic variants in Caucasian systemic lupus erythematosus patients suggests an effect of the combined FcgammaRIIa R/R and IL-1Ra 2/2 genotypes on disease susceptibility.
Jönsen A, Bengtsson AA, Sturfelt G, Truedsson L. Jönsen A, et al. Among authors: sturfelt g. Arthritis Res Ther. 2004;6(6):R557-62. doi: 10.1186/ar1224. Epub 2004 Sep 23. Arthritis Res Ther. 2004. PMID: 15535834 Free PMC article.
Polymorphisms in the tyrosine kinase 2 and interferon regulatory factor 5 genes are associated with systemic lupus erythematosus.
Sigurdsson S, Nordmark G, Göring HH, Lindroos K, Wiman AC, Sturfelt G, Jönsen A, Rantapää-Dahlqvist S, Möller B, Kere J, Koskenmies S, Widén E, Eloranta ML, Julkunen H, Kristjansdottir H, Steinsson K, Alm G, Rönnblom L, Syvänen AC. Sigurdsson S, et al. Among authors: sturfelt g. Am J Hum Genet. 2005 Mar;76(3):528-37. doi: 10.1086/428480. Epub 2005 Jan 18. Am J Hum Genet. 2005. PMID: 15657875 Free PMC article.
Comprehensive evaluation of the genetic variants of interferon regulatory factor 5 (IRF5) reveals a novel 5 bp length polymorphism as strong risk factor for systemic lupus erythematosus.
Sigurdsson S, Göring HH, Kristjansdottir G, Milani L, Nordmark G, Sandling JK, Eloranta ML, Feng D, Sangster-Guity N, Gunnarsson I, Svenungsson E, Sturfelt G, Jönsen A, Truedsson L, Barnes BJ, Alm G, Rönnblom L, Syvänen AC. Sigurdsson S, et al. Among authors: sturfelt g. Hum Mol Genet. 2008 Mar 15;17(6):872-81. doi: 10.1093/hmg/ddm359. Epub 2007 Dec 6. Hum Mol Genet. 2008. PMID: 18063667
275 results