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Salivary antigen-5/CAP family members are Cu2+-dependent antioxidant enzymes that scavenge O₂₋. and inhibit collagen-induced platelet aggregation and neutrophil oxidative burst.
Assumpção TCF, Ma D, Schwarz A, Reiter K, Santana JM, Andersen JF, Ribeiro JMC, Nardone G, Yu LL, Francischetti IMB. Assumpção TCF, et al. Among authors: ma d. J Biol Chem. 2013 May 17;288(20):14341-14361. doi: 10.1074/jbc.M113.466995. Epub 2013 Apr 5. J Biol Chem. 2013. PMID: 23564450 Free PMC article.
Tempol, an intracellular antioxidant, inhibits tissue factor expression, attenuates dendritic cell function, and is partially protective in a murine model of cerebral malaria.
Francischetti IM, Gordon E, Bizzarro B, Gera N, Andrade BB, Oliveira F, Ma D, Assumpção TC, Ribeiro JM, Pena M, Qi CF, Diouf A, Moretz SE, Long CA, Ackerman HC, Pierce SK, Sá-Nunes A, Waisberg M. Francischetti IM, et al. Among authors: ma d. PLoS One. 2014 Feb 28;9(2):e87140. doi: 10.1371/journal.pone.0087140. eCollection 2014. PLoS One. 2014. PMID: 24586264 Free PMC article.
Plasmodium falciparum infection induces expression of a mosquito salivary protein (Agaphelin) that targets neutrophil function and inhibits thrombosis without impairing hemostasis.
Waisberg M, Molina-Cruz A, Mizurini DM, Gera N, Sousa BC, Ma D, Leal AC, Gomes T, Kotsyfakis M, Ribeiro JM, Lukszo J, Reiter K, Porcella SF, Oliveira CJ, Monteiro RQ, Barillas-Mury C, Pierce SK, Francischetti IM. Waisberg M, et al. Among authors: ma d. PLoS Pathog. 2014 Sep 11;10(9):e1004338. doi: 10.1371/journal.ppat.1004338. eCollection 2014 Sep. PLoS Pathog. 2014. PMID: 25211214 Free PMC article.
In Vitro Mode of Action and Anti-thrombotic Activity of Boophilin, a Multifunctional Kunitz Protease Inhibitor from the Midgut of a Tick Vector of Babesiosis, Rhipicephalus microplus.
Assumpção TC, Ma D, Mizurini DM, Kini RM, Ribeiro JM, Kotsyfakis M, Monteiro RQ, Francischetti IM. Assumpção TC, et al. Among authors: ma d. PLoS Negl Trop Dis. 2016 Jan 8;10(1):e0004298. doi: 10.1371/journal.pntd.0004298. eCollection 2016 Jan. PLoS Negl Trop Dis. 2016. PMID: 26745503 Free PMC article.
9,146 results