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Expression of a functional CCR2 receptor enhances tumor localization and tumor eradication by retargeted human T cells expressing a mesothelin-specific chimeric antibody receptor.
Moon EK, Carpenito C, Sun J, Wang LC, Kapoor V, Predina J, Powell DJ Jr, Riley JL, June CH, Albelda SM. Moon EK, et al. Among authors: wang lc. Clin Cancer Res. 2011 Jul 15;17(14):4719-30. doi: 10.1158/1078-0432.CCR-11-0351. Epub 2011 May 24. Clin Cancer Res. 2011. PMID: 21610146 Free PMC article.
Targeting fibroblast activation protein in tumor stroma with chimeric antigen receptor T cells can inhibit tumor growth and augment host immunity without severe toxicity.
Wang LC, Lo A, Scholler J, Sun J, Majumdar RS, Kapoor V, Antzis M, Cotner CE, Johnson LA, Durham AC, Solomides CC, June CH, Puré E, Albelda SM. Wang LC, et al. Cancer Immunol Res. 2014 Feb;2(2):154-66. doi: 10.1158/2326-6066.CIR-13-0027. Epub 2013 Nov 12. Cancer Immunol Res. 2014. PMID: 24778279 Free PMC article.
CCL2 blockade augments cancer immunotherapy.
Fridlender ZG, Buchlis G, Kapoor V, Cheng G, Sun J, Singhal S, Crisanti MC, Wang LC, Heitjan D, Snyder LA, Albelda SM. Fridlender ZG, et al. Among authors: wang lc. Cancer Res. 2010 Jan 1;70(1):109-18. doi: 10.1158/0008-5472.CAN-09-2326. Epub 2009 Dec 22. Cancer Res. 2010. PMID: 20028856 Free PMC article.
1,261 results