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A pyrrolo-pyrimidine derivative targets human primary AML stem cells in vivo.
Sci Transl Med. 2013 Apr 17;5(181):181ra52. doi: 10.1126/scitranslmed.3004387.
Sci Transl Med. 2013.
PMID: 23596204
Overcoming mutational complexity in acute myeloid leukemia by inhibition of critical pathways.
Saito Y, Mochizuki Y, Ogahara I, Watanabe T, Hogdal L, Takagi S, Sato K, Kaneko A, Kajita H, Uchida N, Fukami T, Shultz LD, Taniguchi S, Ohara O, Letai AG, Ishikawa F.
Saito Y, et al. Among authors: ogahara i.
Sci Transl Med. 2017 Oct 25;9(413):eaao1214. doi: 10.1126/scitranslmed.aao1214.
Sci Transl Med. 2017.
PMID: 29070697
Free PMC article.
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Targeting critical kinases and anti-apoptotic molecules overcomes steroid resistance in MLL-rearranged leukaemia.
de Groot AP, Saito Y, Kawakami E, Hashimoto M, Aoki Y, Ono R, Ogahara I, Fujiki S, Kaneko A, Sato K, Kajita H, Watanabe T, Takagi M, Tomizawa D, Koh K, Eguchi M, Ishii E, Ohara O, Shultz LD, Mizutani S, Ishikawa F.
de Groot AP, et al. Among authors: ogahara i.
EBioMedicine. 2021 Feb;64:103235. doi: 10.1016/j.ebiom.2021.103235. Epub 2021 Feb 10.
EBioMedicine. 2021.
PMID: 33581643
Free PMC article.
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Combined inhibition of XIAP and BCL2 drives maximal therapeutic efficacy in genetically diverse aggressive acute myeloid leukemia.
Hashimoto M, Saito Y, Nakagawa R, Ogahara I, Takagi S, Takata S, Amitani H, Endo M, Yuki H, Ramilowski JA, Severin J, Manabe RI, Watanabe T, Ozaki K, Kaneko A, Kajita H, Fujiki S, Sato K, Honma T, Uchida N, Fukami T, Okazaki Y, Ohara O, Shultz LD, Yamada M, Taniguchi S, Vyas P, de Hoon M, Momozawa Y, Ishikawa F.
Hashimoto M, et al. Among authors: ogahara i.
Nat Cancer. 2021 Mar;2(3):340-356. doi: 10.1038/s43018-021-00177-w. Epub 2021 Mar 18.
Nat Cancer. 2021.
PMID: 35121960
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Sphingosine 1-phosphate dependence in the regulation of lymphocyte trafficking to the gut epithelium.
Kunisawa J, Kurashima Y, Higuchi M, Gohda M, Ishikawa I, Ogahara I, Kim N, Shimizu M, Kiyono H.
Kunisawa J, et al. Among authors: ogahara i.
J Exp Med. 2007 Oct 1;204(10):2335-48. doi: 10.1084/jem.20062446. Epub 2007 Sep 17.
J Exp Med. 2007.
PMID: 17875673
Free PMC article.
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Sphingosine 1-phosphate regulates the egress of IgA plasmablasts from Peyer's patches for intestinal IgA responses.
Gohda M, Kunisawa J, Miura F, Kagiyama Y, Kurashima Y, Higuchi M, Ishikawa I, Ogahara I, Kiyono H.
Gohda M, et al. Among authors: ogahara i.
J Immunol. 2008 Apr 15;180(8):5335-43. doi: 10.4049/jimmunol.180.8.5335.
J Immunol. 2008.
PMID: 18390715
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Sphingosine 1-phosphate regulates peritoneal B-cell trafficking for subsequent intestinal IgA production.
Kunisawa J, Kurashima Y, Gohda M, Higuchi M, Ishikawa I, Miura F, Ogahara I, Kiyono H.
Kunisawa J, et al. Among authors: ogahara i.
Blood. 2007 May 1;109(9):3749-56. doi: 10.1182/blood-2006-08-041582. Epub 2007 Jan 18.
Blood. 2007.
PMID: 17234743
Free article.
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Leptin enhances survival and induces migration, degranulation, and cytokine synthesis of human basophils.
Suzukawa M, Nagase H, Ogahara I, Han K, Tashimo H, Shibui A, Koketsu R, Nakae S, Yamaguchi M, Ohta K.
Suzukawa M, et al. Among authors: ogahara i.
J Immunol. 2011 May 1;186(9):5254-60. doi: 10.4049/jimmunol.1004054. Epub 2011 Mar 18.
J Immunol. 2011.
PMID: 21421855
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