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PI3K/mTOR inhibitor PF-04691502 antitumor activity is enhanced with induction of wild-type TP53 in human xenograft and murine knockout models of head and neck cancer.
Herzog A, Bian Y, Vander Broek R, Hall B, Coupar J, Cheng H, Sowers AL, Cook JD, Mitchell JB, Chen Z, Kulkarni AB, Van Waes C. Herzog A, et al. Among authors: chen z. Clin Cancer Res. 2013 Jul 15;19(14):3808-19. doi: 10.1158/1078-0432.CCR-12-2716. Epub 2013 May 2. Clin Cancer Res. 2013. PMID: 23640975 Free PMC article.
A pilot study of longitudinal serum cytokine and angiogenesis factor levels as markers of therapeutic response and survival in patients with head and neck squamous cell carcinoma.
Druzgal CH, Chen Z, Yeh NT, Thomas GR, Ondrey FG, Duffey DC, Vilela RJ, Ende K, McCullagh L, Rudy SF, Muir C, Herscher LL, Morris JC, Albert PS, Van Waes C. Druzgal CH, et al. Among authors: chen z. Head Neck. 2005 Sep;27(9):771-84. doi: 10.1002/hed.20246. Head Neck. 2005. PMID: 15920746
Inhibition of nuclear factor-kappaB and target genes during combined therapy with proteasome inhibitor bortezomib and reirradiation in patients with recurrent head-and-neck squamous cell carcinoma.
Van Waes C, Chang AA, Lebowitz PF, Druzgal CH, Chen Z, Elsayed YA, Sunwoo JB, Rudy SF, Morris JC, Mitchell JB, Camphausen K, Gius D, Adams J, Sausville EA, Conley BA. Van Waes C, et al. Among authors: chen z. Int J Radiat Oncol Biol Phys. 2005 Dec 1;63(5):1400-12. doi: 10.1016/j.ijrobp.2005.05.007. Epub 2005 Jul 11. Int J Radiat Oncol Biol Phys. 2005. PMID: 16005577
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