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Page 1
DCIR interacts with ligands from both endogenous and pathogenic origin.
Bloem K, Vuist IM, van den Berk M, Klaver EJ, van Die I, Knippels LM, Garssen J, García-Vallejo JJ, van Vliet SJ, van Kooyk Y. Bloem K, et al. Among authors: vuist im. Immunol Lett. 2014 Mar-Apr;158(1-2):33-41. doi: 10.1016/j.imlet.2013.11.007. Epub 2013 Nov 14. Immunol Lett. 2014. PMID: 24239607
Human T cell activation results in extracellular signal-regulated kinase (ERK)-calcineurin-dependent exposure of Tn antigen on the cell surface and binding of the macrophage galactose-type lectin (MGL).
van Vliet SJ, Vuist IM, Lenos K, Tefsen B, Kalay H, García-Vallejo JJ, van Kooyk Y. van Vliet SJ, et al. Among authors: vuist im. J Biol Chem. 2013 Sep 20;288(38):27519-27532. doi: 10.1074/jbc.M113.471045. Epub 2013 Aug 5. J Biol Chem. 2013. PMID: 23918927 Free PMC article.
MGL ligand expression is correlated to BRAF mutation and associated with poor survival of stage III colon cancer patients.
Lenos K, Goos JA, Vuist IM, den Uil SH, Delis-van Diemen PM, Belt EJ, Stockmann HB, Bril H, de Wit M, Carvalho B, Giblett S, Pritchard CA, Meijer GA, van Kooyk Y, Fijneman RJ, van Vliet SJ. Lenos K, et al. Among authors: vuist im. Oncotarget. 2015 Sep 22;6(28):26278-90. doi: 10.18632/oncotarget.4495. Oncotarget. 2015. PMID: 26172302 Free PMC article.
Identification of a secondary binding site in human macrophage galactose-type lectin by microarray studies: Implications for the molecular recognition of its ligands.
Marcelo F, Supekar N, Corzana F, van der Horst JC, Vuist IM, Live D, Boons GPH, Smith DF, van Vliet SJ. Marcelo F, et al. Among authors: vuist im. J Biol Chem. 2019 Jan 25;294(4):1300-1311. doi: 10.1074/jbc.RA118.004957. Epub 2018 Nov 30. J Biol Chem. 2019. PMID: 30504228 Free PMC article.