Ng FM - Search Results

1

Fragment-based ligand design of novel potent inhibitors of tankyrases.

Larsson EA, Jansson A, Ng FM, Then SW, Panicker R, Liu B, Sangthongpitag K, Pendharkar V, Tai SJ, Hill J, Dan C, Ho SY, Cheong WW, Poulsen A, Blanchard S, Lin GR, Alam J, Keller TH, Nordlund P. Larsson EA, et al. Among authors: ng fm. J Med Chem. 2013 Jun 13;56(11):4497-508. doi: 10.1021/jm400211f. Epub 2013 Jun 4. J Med Chem. 2013. PMID: 23672613

2

Discovery of dual GyrB/ParE inhibitors active against Gram-negative bacteria.

Ho SY, Wang W, Ng FM, Wong YX, Poh ZY, Tan SWE, Ang SH, Liew SS, Joyner Wong YS, Tan Y, Poulsen A, Pendharkar V, Sangthongpitag K, Manchester J, Basarab G, Hill J, Keller TH, Cherian J. Ho SY, et al. Among authors: ng fm. Eur J Med Chem. 2018 Sep 5;157:610-621. doi: 10.1016/j.ejmech.2018.08.025. Epub 2018 Aug 11. Eur J Med Chem. 2018. PMID: 30125722

3

Peptidomimetic ethyl propenoate covalent inhibitors of the enterovirus 71 3C protease: a P2-P4 study.

Ang MJ, Lau QY, Ng FM, Then SW, Poulsen A, Cheong YK, Ngoh ZX, Tan YW, Peng J, Keller TH, Hill J, Chu JJ, Chia CS. Ang MJ, et al. Among authors: ng fm. J Enzyme Inhib Med Chem. 2016;31(2):332-9. doi: 10.3109/14756366.2015.1018245. Epub 2015 Sep 4. J Enzyme Inhib Med Chem. 2016. PMID: 25792507

4

Escherichia coli Topoisomerase IV E Subunit and an Inhibitor Binding Mode Revealed by NMR Spectroscopy.

Li Y, Wong YL, Ng FM, Liu B, Wong YX, Poh ZY, Liu S, Then SW, Lee MY, Ng HQ, Huang Q, Hung AW, Cherian J, Hill J, Keller TH, Kang C. Li Y, et al. Among authors: ng fm, ng hq. J Biol Chem. 2016 Aug 19;291(34):17743-53. doi: 10.1074/jbc.M116.737429. Epub 2016 Jun 30. J Biol Chem. 2016. PMID: 27365392 Free PMC article.

5

Characterization of the interaction between Escherichia coli topoisomerase IV E subunit and an ATP competitive inhibitor.

Li Y, Wong YL, Ng FM, Liu B, Wong YX, Poh ZY, Then SW, Lee MY, Ng HQ, Hung AW, Cherian J, Hill J, Keller TH, Kang C. Li Y, et al. Among authors: ng fm, ng hq. Biochem Biophys Res Commun. 2015 Nov 27;467(4):961-6. doi: 10.1016/j.bbrc.2015.10.036. Epub 2015 Oct 17. Biochem Biophys Res Commun. 2015. PMID: 26471301

6

Discovery of an ultra-short linear antibacterial tetrapeptide with anti-MRSA activity from a structure-activity relationship study.

Lau QY, Ng FM, Cheong JW, Yap YY, Tan YY, Jureen R, Hill J, Chia CS. Lau QY, et al. Among authors: ng fm. Eur J Med Chem. 2015 Nov 13;105:138-44. doi: 10.1016/j.ejmech.2015.10.015. Epub 2015 Oct 22. Eur J Med Chem. 2015. PMID: 26489599

7

Miniature bovine pancreatic trypsin inhibitors (m-BPTIs) of the West Nile virus NS2B-NS3 protease.

Ang MJ, Lim HA, Poulsen A, Wee JL, Ng FM, Joy J, Hill J, Chia CS. Ang MJ, et al. Among authors: ng fm. J Enzyme Inhib Med Chem. 2016;31(sup2):194-200. doi: 10.1080/14756366.2016.1190713. Epub 2016 May 31. J Enzyme Inhib Med Chem. 2016. PMID: 27241372

8

Antiviral activities of peptide-based covalent inhibitors of the Enterovirus 71 3C protease.

Tan YW, Ang MJ, Lau QY, Poulsen A, Ng FM, Then SW, Peng J, Hill J, Hong WJ, Chia CS, Chu JJ. Tan YW, et al. Among authors: ng fm. Sci Rep. 2016 Sep 20;6:33663. doi: 10.1038/srep33663. Sci Rep. 2016. PMID: 27645381 Free PMC article.

9

Structure-activity relationship studies of ultra-short peptides with potent activities against fluconazole-resistant Candida albicans.

Ng SMS, Yap JM, Lau QY, Ng FM, Ong EHQ, Barkham T, Teo JWP, Alfatah M, Kong KW, Hoon S, Arumugam P, Hill J, Brian Chia CS. Ng SMS, et al. Among authors: ng fm. Eur J Med Chem. 2018 Apr 25;150:479-490. doi: 10.1016/j.ejmech.2018.03.027. Epub 2018 Mar 9. Eur J Med Chem. 2018. PMID: 29549835

10

Application of Fragment-Based Drug Discovery against DNA Gyrase B.

Chen GY, Ng FM, Tan YW, Poulsen A, Seetoh W, Lin G, Kang C, Then SW, Ahmad NH, Wong YL, Ng HQ, Chia CSB, Lau QY, Hill J, Hung AW, Keller TH. Chen GY, et al. Among authors: ng fm, ng hq. Chempluschem. 2015 Aug;80(8):1250-1254. doi: 10.1002/cplu.201500197. Epub 2015 Jun 24. Chempluschem. 2015. PMID: 31973307

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