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The two faces of potent antitumor duocarmycin-based drugs: a structural dissection reveals disparate motifs for DNA versus aldehyde dehydrogenase 1 affinity.
Angew Chem Int Ed Engl. 2013 Jul 1;52(27):6921-5. doi: 10.1002/anie.201208941. Epub 2013 May 16.
Angew Chem Int Ed Engl. 2013.
PMID: 23681547
No abstract available.
Structural, Biochemical, and Computational Studies Reveal the Mechanism of Selective Aldehyde Dehydrogenase 1A1 Inhibition by Cytotoxic Duocarmycin Analogues.
Koch MF, Harteis S, Blank ID, Pestel G, Tietze LF, Ochsenfeld C, Schneider S, Sieber SA.
Koch MF, et al.
Angew Chem Int Ed Engl. 2015 Nov 9;54(46):13550-4. doi: 10.1002/anie.201505749. Epub 2015 Sep 16.
Angew Chem Int Ed Engl. 2015.
PMID: 26373694
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Synthesis, biological evaluation, and live cell imaging of novel fluorescent duocarmycin analogs.
Tietze LF, Behrendt F, Pestel GF, Schuberth I, Mitkovski M.
Tietze LF, et al. Among authors: pestel gf.
Chem Biodivers. 2012 Nov;9(11):2559-70. doi: 10.1002/cbdv.201200289.
Chem Biodivers. 2012.
PMID: 23161634
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