Flynn G - Search Results

1

AqF026 is a pharmacologic agonist of the water channel aquaporin-1.

Yool AJ, Morelle J, Cnops Y, Verbavatz JM, Campbell EM, Beckett EA, Booker GW, Flynn G, Devuyst O. Yool AJ, et al. Among authors: flynn g. J Am Soc Nephrol. 2013 Jun;24(7):1045-52. doi: 10.1681/ASN.2012080869. Epub 2013 Jun 6. J Am Soc Nephrol. 2013. PMID: 23744886 Free PMC article.

2

Bumetanide Derivatives AqB007 and AqB011 Selectively Block the Aquaporin-1 Ion Channel Conductance and Slow Cancer Cell Migration.

Kourghi M, Pei JV, De Ieso ML, Flynn G, Yool AJ. Kourghi M, et al. Among authors: flynn g. Mol Pharmacol. 2016 Jan;89(1):133-40. doi: 10.1124/mol.115.101618. Epub 2015 Oct 14. Mol Pharmacol. 2016. PMID: 26467039 Free PMC article.

3

Inhibition of aquaporin-1 and aquaporin-4 water permeability by a derivative of the loop diuretic bumetanide acting at an internal pore-occluding binding site.

Migliati E, Meurice N, DuBois P, Fang JS, Somasekharan S, Beckett E, Flynn G, Yool AJ. Migliati E, et al. Among authors: flynn g. Mol Pharmacol. 2009 Jul;76(1):105-12. doi: 10.1124/mol.108.053744. Epub 2009 Apr 29. Mol Pharmacol. 2009. PMID: 19403703 Free PMC article.

4

Roles for novel pharmacological blockers of aquaporins in the treatment of brain oedema and cancer.

Yool AJ, Brown EA, Flynn GA. Yool AJ, et al. Clin Exp Pharmacol Physiol. 2010 Apr;37(4):403-9. doi: 10.1111/j.1440-1681.2009.05244.x. Epub 2009 Jun 29. Clin Exp Pharmacol Physiol. 2010. PMID: 19566827 Review.

5

Characterization of novel diaryl oxazole-based compounds as potential agents to treat pancreatic cancer.

Shaw AY, Henderson MC, Flynn G, Samulitis B, Han H, Stratton SP, Chow HH, Hurley LH, Dorr RT. Shaw AY, et al. Among authors: flynn g. J Pharmacol Exp Ther. 2009 Nov;331(2):636-47. doi: 10.1124/jpet.109.156406. Epub 2009 Aug 5. J Pharmacol Exp Ther. 2009. PMID: 19657049 Free PMC article.

6

UA62784, a novel inhibitor of centromere protein E kinesin-like protein.

Henderson MC, Shaw YJ, Wang H, Han H, Hurley LH, Flynn G, Dorr RT, Von Hoff DD. Henderson MC, et al. Among authors: flynn g. Mol Cancer Ther. 2009 Jan;8(1):36-44. doi: 10.1158/1535-7163.MCT-08-0789. Mol Cancer Ther. 2009. PMID: 19139111 Free PMC article.

7

Application of a novel [3+2] cycloaddition reaction to prepare substituted imidazoles and their use in the design of potent DFG-out allosteric B-Raf inhibitors.

Dietrich J, Gokhale V, Wang X, Hurley LH, Flynn GA. Dietrich J, et al. Bioorg Med Chem. 2010 Jan 1;18(1):292-304. doi: 10.1016/j.bmc.2009.10.055. Epub 2009 Nov 11. Bioorg Med Chem. 2010. PMID: 19962319

8

3,5-Diaryl-1H-pyrazole as a molecular scaffold for the synthesis of apoptosis-inducing agents.

Shaw AY, Liau HH, Lu PJ, Yang CN, Lee CH, Chen JY, Xu Z, Flynn G. Shaw AY, et al. Among authors: flynn g. Bioorg Med Chem. 2010 May 1;18(9):3270-8. doi: 10.1016/j.bmc.2010.03.016. Epub 2010 Mar 16. Bioorg Med Chem. 2010. PMID: 20381360

9

Synthesis and pharmacological evaluation of N-(3-(1H-indol-4-yl)-5-(2-methoxyisonicotinoyl)phenyl)methanesulfonamide (LP-261), a potent antimitotic agent.

Shetty RS, Lee Y, Liu B, Husain A, Joseph RW, Lu Y, Nelson D, Mihelcic J, Chao W, Moffett KK, Schumacher A, Flubacher D, Stojanovic A, Bukhtiyarova M, Williams K, Lee KJ, Ochman AR, Saporito MS, Moore WR, Flynn GA, Dorsey BD, Springman EB, Fujimoto T, Kelly MJ. Shetty RS, et al. J Med Chem. 2011 Jan 13;54(1):179-200. doi: 10.1021/jm100659v. Epub 2010 Dec 2. J Med Chem. 2011. PMID: 21126027

10

Two classes of p38alpha MAP kinase inhibitors having a common diphenylether core but exhibiting divergent binding modes.

Michelotti EL, Moffett KK, Nguyen D, Kelly MJ, Shetty R, Chai X, Northrop K, Namboodiri V, Campbell B, Flynn GA, Fujimoto T, Hollinger FP, Bukhtiyarova M, Springman EB, Karpusas M. Michelotti EL, et al. Bioorg Med Chem Lett. 2005 Dec 1;15(23):5274-9. doi: 10.1016/j.bmcl.2005.08.038. Epub 2005 Sep 19. Bioorg Med Chem Lett. 2005. PMID: 16169718

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

417 results

Search Page