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Agouti-related peptide-expressing neurons are mandatory for feeding.
Gropp E, Shanabrough M, Borok E, Xu AW, Janoschek R, Buch T, Plum L, Balthasar N, Hampel B, Waisman A, Barsh GS, Horvath TL, Brüning JC. Gropp E, et al. Among authors: horvath tl. Nat Neurosci. 2005 Oct;8(10):1289-91. doi: 10.1038/nn1548. Epub 2005 Sep 11. Nat Neurosci. 2005. PMID: 16158063
Enhanced PIP3 signaling in POMC neurons causes KATP channel activation and leads to diet-sensitive obesity.
Plum L, Ma X, Hampel B, Balthasar N, Coppari R, Münzberg H, Shanabrough M, Burdakov D, Rother E, Janoschek R, Alber J, Belgardt BF, Koch L, Seibler J, Schwenk F, Fekete C, Suzuki A, Mak TW, Krone W, Horvath TL, Ashcroft FM, Brüning JC. Plum L, et al. Among authors: horvath tl. J Clin Invest. 2006 Jul;116(7):1886-901. doi: 10.1172/JCI27123. Epub 2006 Jun 22. J Clin Invest. 2006. PMID: 16794735 Free PMC article.
STAT3 inhibition of gluconeogenesis is downregulated by SirT1.
Nie Y, Erion DM, Yuan Z, Dietrich M, Shulman GI, Horvath TL, Gao Q. Nie Y, et al. Among authors: horvath tl. Nat Cell Biol. 2009 Apr;11(4):492-500. doi: 10.1038/ncb1857. Epub 2009 Mar 22. Nat Cell Biol. 2009. PMID: 19295512 Free PMC article.
GABA keeps up an appetite for life.
Dietrich MO, Horvath TL. Dietrich MO, et al. Among authors: horvath tl. Cell. 2009 Jun 26;137(7):1177-9. doi: 10.1016/j.cell.2009.06.002. Cell. 2009. PMID: 19563747 Free article.
The role of mitochondrial uncoupling proteins in lifespan.
Dietrich MO, Horvath TL. Dietrich MO, et al. Among authors: horvath tl. Pflugers Arch. 2010 Jan;459(2):269-75. doi: 10.1007/s00424-009-0729-0. Epub 2009 Sep 17. Pflugers Arch. 2010. PMID: 19760284 Free PMC article. Review.
376 results