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Tau-amyloid interactions in the rTgTauEC model of early Alzheimer's disease suggest amyloid-induced disruption of axonal projections and exacerbated axonal pathology.
Pooler AM, Polydoro M, Wegmann SK, Pitstick R, Kay KR, Sanchez L, Carlson GA, Gomez-Isla T, Albers MW, Spires-Jones TL, Hyman BT. Pooler AM, et al. Among authors: carlson ga. J Comp Neurol. 2013 Dec 15;521(18):4236-48. doi: 10.1002/cne.23411. J Comp Neurol. 2013. PMID: 23839581 Free PMC article.
Caspase activation precedes and leads to tangles.
de Calignon A, Fox LM, Pitstick R, Carlson GA, Bacskai BJ, Spires-Jones TL, Hyman BT. de Calignon A, et al. Among authors: carlson ga. Nature. 2010 Apr 22;464(7292):1201-4. doi: 10.1038/nature08890. Epub 2010 Mar 31. Nature. 2010. PMID: 20357768 Free PMC article.
Scavenger receptor CD36 is essential for the cerebrovascular oxidative stress and neurovascular dysfunction induced by amyloid-beta.
Park L, Wang G, Zhou P, Zhou J, Pitstick R, Previti ML, Younkin L, Younkin SG, Van Nostrand WE, Cho S, Anrather J, Carlson GA, Iadecola C. Park L, et al. Among authors: carlson ga. Proc Natl Acad Sci U S A. 2011 Mar 22;108(12):5063-8. doi: 10.1073/pnas.1015413108. Epub 2011 Mar 7. Proc Natl Acad Sci U S A. 2011. PMID: 21383152 Free PMC article.
426 results