Lawrence KM - Search Results

1

Urocortin protects chondrocytes from NO-induced apoptosis: a future therapy for osteoarthritis?

Intekhab-Alam NY, White OB, Getting SJ, Petsa A, Knight RA, Chowdrey HS, Townsend PA, Lawrence KM, Locke IC. Intekhab-Alam NY, et al. Among authors: lawrence km. Cell Death Dis. 2013 Jul 11;4(7):e717. doi: 10.1038/cddis.2013.231. Cell Death Dis. 2013. PMID: 23846219 Free PMC article.

2

Urocortin--from Parkinson's disease to the skeleton.

Lawrence KM, Jackson TR, Jamieson D, Stevens A, Owens G, Sayan BS, Locke IC, Townsend PA. Lawrence KM, et al. Int J Biochem Cell Biol. 2015 Mar;60:130-8. doi: 10.1016/j.biocel.2014.12.005. Epub 2014 Dec 23. Int J Biochem Cell Biol. 2015. PMID: 25541373 Review.

3

Chondroprotection by urocortin involves blockade of the mechanosensitive ion channel Piezo1.

Lawrence KM, Jones RC, Jackson TR, Baylie RL, Abbott B, Bruhn-Olszewska B, Board TN, Locke IC, Richardson SM, Townsend PA. Lawrence KM, et al. Sci Rep. 2017 Jul 11;7(1):5147. doi: 10.1038/s41598-017-04367-4. Sci Rep. 2017. PMID: 28698554 Free PMC article.

4

New targets of urocortin-mediated cardioprotection.

Barry SP, Lawrence KM, McCormick J, Soond SM, Hubank M, Eaton S, Sivarajah A, Scarabelli TM, Knight RA, Thiemermann C, Latchman DS, Townsend PA, Stephanou A. Barry SP, et al. Among authors: lawrence km. J Mol Endocrinol. 2010 Aug;45(2):69-85. doi: 10.1677/JME-09-0148. Epub 2010 May 25. J Mol Endocrinol. 2010. PMID: 20501665 Free PMC article.

5

Urocortin is a novel regulator of osteoclast differentiation and function through inhibition of a canonical transient receptor potential 1-like cation channel.

Combs CE, Fuller K, Kumar H, Albert AP, Pirianov G, McCormick J, Locke IC, Chambers TJ, Lawrence KM. Combs CE, et al. Among authors: lawrence km. J Endocrinol. 2012 Feb;212(2):187-97. doi: 10.1530/JOE-11-0254. Epub 2011 Nov 14. J Endocrinol. 2012. PMID: 22083217

6

K(ATP) channel gene expression is induced by urocortin and mediates its cardioprotective effect.

Lawrence KM, Chanalaris A, Scarabelli T, Hubank M, Pasini E, Townsend PA, Comini L, Ferrari R, Tinker A, Stephanou A, Knight RA, Latchman DS. Lawrence KM, et al. Circulation. 2002 Sep 17;106(12):1556-62. doi: 10.1161/01.cir.0000028424.02525.ae. Circulation. 2002. PMID: 12234964 Free article.

7

Urocortin protects cardiac myocytes from ischemia/reperfusion injury by attenuating calcium-insensitive phospholipase A2 gene expression.

Lawrence KM, Scarabelli TM, Turtle L, Chanalaris A, Townsend PA, Carroll CJ, Hubank M, Stephanou A, Knight RA, Latchman DS. Lawrence KM, et al. FASEB J. 2003 Dec;17(15):2313-5. doi: 10.1096/fj.02-0832fje. Epub 2003 Oct 16. FASEB J. 2003. PMID: 14563694

8

Cardioprotection mediated by urocortin is dependent on PKCepsilon activation.

Lawrence KM, Kabir AM, Bellahcene M, Davidson S, Cao XB, McCormick J, Mesquita RA, Carroll CJ, Chanalaris A, Townsend PA, Hubank M, Stephanou A, Knight RA, Marber MS, Latchman DS. Lawrence KM, et al. FASEB J. 2005 May;19(7):831-3. doi: 10.1096/fj.04-2506fje. Epub 2005 Mar 10. FASEB J. 2005. PMID: 15764590

9

The cardioprotective effect of urocortin during ischaemia/reperfusion involves the prevention of mitochondrial damage.

Lawrence KM, Townsend PA, Davidson SM, Carroll CJ, Eaton S, Hubank M, Knight RA, Stephanou A, Latchman DS. Lawrence KM, et al. Biochem Biophys Res Commun. 2004 Aug 20;321(2):479-86. doi: 10.1016/j.bbrc.2004.06.170. Biochem Biophys Res Commun. 2004. PMID: 15358201

10

Hypertrophic effects of urocortin homologous peptides are mediated via activation of the Akt pathway.

Chanalaris A, Lawrence KM, Townsend PA, Davidson S, Jamshidi Y, Stephanou A, Knight RD, Hsu SY, Hsueh AJ, Latchman DS. Chanalaris A, et al. Among authors: lawrence km. Biochem Biophys Res Commun. 2005 Mar 11;328(2):442-8. doi: 10.1016/j.bbrc.2005.01.001. Biochem Biophys Res Commun. 2005. PMID: 15694367

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