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Identification of GNE-293, a potent and selective PI3Kδ inhibitor: navigating in vitro genotoxicity while improving potency and selectivity.
Safina BS, Sweeney ZK, Li J, Chan BK, Bisconte A, Carrera D, Castanedo G, Flagella M, Heald R, Lewis C, Murray JM, Nonomiya J, Pang J, Price S, Reif K, Salphati L, Seward EM, Wei B, Sutherlin DP. Safina BS, et al. Among authors: carrera d. Bioorg Med Chem Lett. 2013 Sep 1;23(17):4953-9. doi: 10.1016/j.bmcl.2013.06.052. Epub 2013 Jun 29. Bioorg Med Chem Lett. 2013. PMID: 23867164 Free article.
Stereoselective Synthesis of the IDO Inhibitor Navoximod.
St-Jean F, Angelaud R, Bachmann S, Carrera DE, Remarchuk T, Piechowicz KA, Niedermann K, Iding H, Meier R, Hou H, Sirois LE, Xu J, Olbrich M, Rege P, Guillemot-Plass M, Gosselin F. St-Jean F, et al. J Org Chem. 2022 Apr 1;87(7):4955-4960. doi: 10.1021/acs.joc.1c02994. Epub 2022 Mar 23. J Org Chem. 2022. PMID: 35317556
Starfysh integrates spatial transcriptomic and histologic data to reveal heterogeneous tumor-immune hubs.
He S, Jin Y, Nazaret A, Shi L, Chen X, Rampersaud S, Dhillon BS, Valdez I, Friend LE, Fan JL, Park CY, Mintz RL, Lao YH, Carrera D, Fang KW, Mehdi K, Rohde M, McFaline-Figueroa JL, Blei D, Leong KW, Rudensky AY, Plitas G, Azizi E. He S, et al. Among authors: carrera d. Nat Biotechnol. 2024 Mar 21. doi: 10.1038/s41587-024-02173-8. Online ahead of print. Nat Biotechnol. 2024. PMID: 38514799
127 results