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Dissecting the active site of the collagenolytic cathepsin L3 protease of the invasive stage of Fasciola hepatica.
PLoS Negl Trop Dis. 2013 Jul 11;7(7):e2269. doi: 10.1371/journal.pntd.0002269. Print 2013.
PLoS Negl Trop Dis. 2013.
PMID: 23875031
Free PMC article.
The major cathepsin L secreted by the invasive juvenile Fasciola hepatica prefers proline in the S2 subsite and can cleave collagen.
Corvo I, Cancela M, Cappetta M, Pi-Denis N, Tort JF, Roche L.
Corvo I, et al. Among authors: pi denis n.
Mol Biochem Parasitol. 2009 Sep;167(1):41-7. doi: 10.1016/j.molbiopara.2009.04.005. Epub 2009 Apr 19.
Mol Biochem Parasitol. 2009.
PMID: 19383516
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Substrate Specificity of Cysteine Proteases Beyond the S2 Pocket: Mutagenesis and Molecular Dynamics Investigation of Fasciola hepatica Cathepsins L.
Corvo I, Ferraro F, Merlino A, Zuberbühler K, O'Donoghue AJ, Pastro L, Pi-Denis N, Basika T, Roche L, McKerrow JH, Craik CS, Caffrey CR, Tort JF.
Corvo I, et al. Among authors: pi denis n.
Front Mol Biosci. 2018 Apr 19;5:40. doi: 10.3389/fmolb.2018.00040. eCollection 2018.
Front Mol Biosci. 2018.
PMID: 29725596
Free PMC article.
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A novel mutation in the OAR domain of the ARX gene.
Tapie A, Pi-Denis N, Souto J, Vomero A, Peluffo G, Boidi M, Ciganda M, Curbelo N, Raggio V, Roche L, Pastro L.
Tapie A, et al. Among authors: pi denis n.
Clin Case Rep. 2017 Jan 23;5(2):170-174. doi: 10.1002/ccr3.769. eCollection 2017 Feb.
Clin Case Rep. 2017.
PMID: 28174645
Free PMC article.
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