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Statin use is associated with a reduced incidence of colorectal cancer expressing SMAD4.
Ouahoud S, Jacobs RJ, Kodach LL, Voorneveld PW, Hawinkels LJAC, Weil NL, van Vliet B, Herings RM, van der Burg LRA, van Wezel T, Morreau H, Slingerland M, Bastiaannet E, Putter H, Hardwick JCH. Ouahoud S, et al. Among authors: kodach ll. Br J Cancer. 2022 Feb;126(2):297-301. doi: 10.1038/s41416-021-01604-6. Epub 2021 Oct 26. Br J Cancer. 2022. PMID: 34703008 Free PMC article.
The BMP pathway either enhances or inhibits the Wnt pathway depending on the SMAD4 and p53 status in CRC.
Voorneveld PW, Kodach LL, Jacobs RJ, van Noesel CJ, Peppelenbosch MP, Korkmaz KS, Molendijk I, Dekker E, Morreau H, van Pelt GW, Tollenaar RA, Mesker W, Hawinkels LJ, Paauwe M, Verspaget HW, Geraets DT, Hommes DW, Offerhaus GJ, van den Brink GR, Ten Dijke P, Hardwick JC. Voorneveld PW, et al. Among authors: kodach ll. Br J Cancer. 2015 Jan 6;112(1):122-30. doi: 10.1038/bjc.2014.560. Epub 2014 Nov 13. Br J Cancer. 2015. PMID: 25393365 Free PMC article.
Cholesterol metabolism and colorectal cancers.
Jacobs RJ, Voorneveld PW, Kodach LL, Hardwick JC. Jacobs RJ, et al. Among authors: kodach ll. Curr Opin Pharmacol. 2012 Dec;12(6):690-5. doi: 10.1016/j.coph.2012.07.010. Epub 2012 Aug 8. Curr Opin Pharmacol. 2012. PMID: 22884562 Review.
SMAD4 exerts a tumor-promoting role in hepatocellular carcinoma.
Hernanda PY, Chen K, Das AM, Sideras K, Wang W, Li J, Cao W, Bots SJ, Kodach LL, de Man RA, Ijzermans JN, Janssen HL, Stubbs AP, Sprengers D, Bruno MJ, Metselaar HJ, ten Hagen TL, Kwekkeboom J, Peppelenbosch MP, Pan Q. Hernanda PY, et al. Among authors: kodach ll. Oncogene. 2015 Sep 24;34(39):5055-68. doi: 10.1038/onc.2014.425. Epub 2014 Dec 22. Oncogene. 2015. PMID: 25531314
Improving diagnostic accuracy of identifying gastric cancer patients with peritoneal metastases: tumor-guided cell-free DNA analysis of peritoneal fluid.
van der Sluis K, van Sandick JW, Vollebergh MA, van Dieren JM, Hugen N, Hartemink KJ, Veenhof AAFA, Verhoeven E, van den Berg JG, Snaebjornsson P, Noe M, van Wezel T, Boelens MC, Kodach LL. van der Sluis K, et al. Among authors: kodach ll. Oncogene. 2024 Jun;43(24):1877-1882. doi: 10.1038/s41388-024-03034-z. Epub 2024 Apr 23. Oncogene. 2024. PMID: 38654110
Author Correction: Neoadjuvant atezolizumab plus chemotherapy in gastric and gastroesophageal junction adenocarcinoma: the phase 2 PANDA trial.
Verschoor YL, van de Haar J, van den Berg JG, van Sandick JW, Kodach LL, van Dieren JM, Balduzzi S, Grootscholten C, IJsselsteijn ME, Veenhof AAFA, Hartemink KJ, Vollebergh MA, Jurdi A, Sharma S, Spickard E, Owers EC, Bartels-Rutten A, den Hartog P, de Miranda NFCC, van Leerdam ME, Haanen JBAG, Schumacher TN, Voest EE, Chalabi M. Verschoor YL, et al. Among authors: kodach ll. Nat Med. 2024 May;30(5):1499. doi: 10.1038/s41591-024-02898-8. Nat Med. 2024. PMID: 38448792 Free PMC article. No abstract available.
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