Jacob-Hirsch J - Search Results

1

Genome-scale expression and transcription factor binding profiles reveal therapeutic targets in transgenic ERG myeloid leukemia.

Goldberg L, Tijssen MR, Birger Y, Hannah RL, Kinston SJ, Schütte J, Beck D, Knezevic K, Schiby G, Jacob-Hirsch J, Biran A, Kloog Y, Marcucci G, Bloomfield CD, Aplan PD, Pimanda JE, Göttgens B, Izraeli S. Goldberg L, et al. Blood. 2013 Oct 10;122(15):2694-703. doi: 10.1182/blood-2013-01-477133. Epub 2013 Aug 23. Blood. 2013. PMID: 23974202 Free PMC article.

2

Ras inhibition in glioblastoma down-regulates hypoxia-inducible factor-1alpha, causing glycolysis shutdown and cell death.

Blum R, Jacob-Hirsch J, Amariglio N, Rechavi G, Kloog Y. Blum R, et al. Cancer Res. 2005 Feb 1;65(3):999-1006. Cancer Res. 2005. PMID: 15705901

3

Disruption of cooperation between Ras and MycN in human neuroblastoma cells promotes growth arrest.

Yaari S, Jacob-Hirsch J, Amariglio N, Haklai R, Rechavi G, Kloog Y. Yaari S, et al. Clin Cancer Res. 2005 Jun 15;11(12):4321-30. doi: 10.1158/1078-0432.CCR-04-2071. Clin Cancer Res. 2005. PMID: 15958613

4

Molecular pathways regulating pro-migratory effects of Hedgehog signaling.

Hochman E, Castiel A, Jacob-Hirsch J, Amariglio N, Izraeli S. Hochman E, et al. J Biol Chem. 2006 Nov 10;281(45):33860-70. doi: 10.1074/jbc.M605905200. Epub 2006 Aug 30. J Biol Chem. 2006. PMID: 16943197 Free article.

5

Suppression of survivin expression in glioblastoma cells by the Ras inhibitor farnesylthiosalicylic acid promotes caspase-dependent apoptosis.

Blum R, Jacob-Hirsch J, Rechavi G, Kloog Y. Blum R, et al. Mol Cancer Ther. 2006 Sep;5(9):2337-47. doi: 10.1158/1535-7163.MCT-06-0193. Mol Cancer Ther. 2006. PMID: 16985068

6

Gene expression signature of human cancer cell lines treated with the ras inhibitor salirasib (S-farnesylthiosalicylic acid).

Blum R, Elkon R, Yaari S, Zundelevich A, Jacob-Hirsch J, Rechavi G, Shamir R, Kloog Y. Blum R, et al. Cancer Res. 2007 Apr 1;67(7):3320-8. doi: 10.1158/0008-5472.CAN-06-4287. Cancer Res. 2007. PMID: 17409441

7

TNF activates a NF-kappaB-regulated cellular program in human CD45RA- regulatory T cells that modulates their suppressive function.

Nagar M, Jacob-Hirsch J, Vernitsky H, Berkun Y, Ben-Horin S, Amariglio N, Bank I, Kloog Y, Rechavi G, Goldstein I. Nagar M, et al. J Immunol. 2010 Apr 1;184(7):3570-81. doi: 10.4049/jimmunol.0902070. Epub 2010 Feb 24. J Immunol. 2010. PMID: 20181891

8

Trans-SILAC: sorting out the non-cell-autonomous proteome.

Rechavi O, Kalman M, Fang Y, Vernitsky H, Jacob-Hirsch J, Foster LJ, Kloog Y, Goldstein I. Rechavi O, et al. Nat Methods. 2010 Nov;7(11):923-7. doi: 10.1038/nmeth.1513. Epub 2010 Oct 10. Nat Methods. 2010. PMID: 20935649

9

Ras Signaling Inhibitors Attenuate Disease in Adjuvant-Induced Arthritis via Targeting Pathogenic Antigen-Specific Th17-Type Cells.

Zayoud M, Marcu-Malina V, Vax E, Jacob-Hirsch J, Elad-Sfadia G, Barshack I, Kloog Y, Goldstein I. Zayoud M, et al. Front Immunol. 2017 Jul 7;8:799. doi: 10.3389/fimmu.2017.00799. eCollection 2017. Front Immunol. 2017. PMID: 28736556 Free PMC article.

10

In Vivo Expansion of Cancer Stemness Affords Novel Cancer Stem Cell Targets: Malignant Rhabdoid Tumor as an Example.

Golan H, Shukrun R, Caspi R, Vax E, Pode-Shakked N, Goldberg S, Pleniceanu O, Bar-Lev DD, Mark-Danieli M, Pri-Chen S, Jacob-Hirsch J, Kanter I, Trink A, Schiby G, Bilik R, Kalisky T, Harari-Steinberg O, Toren A, Dekel B. Golan H, et al. Stem Cell Reports. 2018 Sep 11;11(3):795-810. doi: 10.1016/j.stemcr.2018.07.010. Epub 2018 Aug 16. Stem Cell Reports. 2018. PMID: 30122444 Free PMC article.

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