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Leukemic transformation driven by an ASXL1 mutation after a JAK2V617F-positive primary myelofibrosis: clonal evolution and hierarchy revealed by next-generation sequencing.
Ferrer-Marín F, Bellosillo B, Martínez-Avilés L, Soler G, Carbonell P, Luengo-Gil G, Caparrós E, Torregrosa JM, Besses C, Vicente V. Ferrer-Marín F, et al. Among authors: martinez aviles l. J Hematol Oncol. 2013 Sep 8;6:68. doi: 10.1186/1756-8722-6-68. J Hematol Oncol. 2013. PMID: 24011025 Free PMC article.
JAK2V617F monitoring in polycythemia vera and essential thrombocythemia: clinical usefulness for predicting myelofibrotic transformation and thrombotic events.
Alvarez-Larrán A, Bellosillo B, Pereira A, Kerguelen A, Hernández-Boluda JC, Martínez-Avilés L, Fernández-Rodríguez C, Gómez M, Lombardía L, Angona A, Ancochea A, Senín A, Longarón R, Navarro B, Collado M, Besses C. Alvarez-Larrán A, et al. Among authors: martinez aviles l. Am J Hematol. 2014 May;89(5):517-23. doi: 10.1002/ajh.23676. Epub 2014 Feb 21. Am J Hematol. 2014. PMID: 24458835 Free article.
Busulfan in patients with polycythemia vera or essential thrombocythemia refractory or intolerant to hydroxyurea.
Alvarez-Larrán A, Martínez-Avilés L, Hernández-Boluda JC, Ferrer-Marín F, Antelo ML, Burgaleta C, Mata MI, Xicoy B, Martínez-Trillos A, Gómez-Casares MT, Durán MA, Marcote B, Ancochea A, Senín A, Angona A, Gómez M, Vicente V, Cervantes F, Bellosillo B, Besses C. Alvarez-Larrán A, et al. Among authors: martinez aviles l. Ann Hematol. 2014 Dec;93(12):2037-43. doi: 10.1007/s00277-014-2152-7. Epub 2014 Jul 2. Ann Hematol. 2014. PMID: 24981691 Clinical Trial.
Hematopoietic clonal dominance, stem cell mutations, and evolutionary pattern of JAK2V617F allele burden in polycythemia vera.
Angona A, Alvarez-Larrán A, Bellosillo B, Martínez-Avilés L, Camacho L, Fernández-Rodríguez C, Pairet S, Longarón R, Ancochea Á, Senín A, Florensa L, Besses C. Angona A, et al. Among authors: martinez aviles l. Eur J Haematol. 2015 Mar;94(3):251-7. doi: 10.1111/ejh.12425. Epub 2014 Sep 13. Eur J Haematol. 2015. PMID: 25082530
WHO-histological criteria for myeloproliferative neoplasms: reproducibility, diagnostic accuracy and correlation with gene mutations and clinical outcomes.
Alvarez-Larrán A, Ancochea A, García M, Climent F, García-Pallarols F, Angona A, Senín A, Barranco C, Martínez-Avilés L, Serrano S, Bellosillo B, Besses C. Alvarez-Larrán A, et al. Among authors: martinez aviles l. Br J Haematol. 2014 Sep;166(6):911-9. doi: 10.1111/bjh.12990. Epub 2014 Jun 24. Br J Haematol. 2014. PMID: 24957246 Free article.
A higher JAK2 V617F-mutated clone is observed in platelets than in granulocytes from essential thrombocythemia patients, but not in patients with polycythemia vera and primary myelofibrosis.
Bellosillo B, Martínez-Avilés L, Gimeno E, Florensa L, Longarón R, Navarro G, Salar A, Espinet B, Solé F, Serrano S, Besses C. Bellosillo B, et al. Leukemia. 2007 Jun;21(6):1331-2. doi: 10.1038/sj.leu.2404649. Epub 2007 Mar 15. Leukemia. 2007. PMID: 17361221 No abstract available.
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