Kelsall IR - Search Results

1

TRIAD1 and HHARI bind to and are activated by distinct neddylated Cullin-RING ligase complexes.

Kelsall IR, Duda DM, Olszewski JL, Hofmann K, Knebel A, Langevin F, Wood N, Wightman M, Schulman BA, Alpi AF. Kelsall IR, et al. EMBO J. 2013 Oct 30;32(21):2848-60. doi: 10.1038/emboj.2013.209. Epub 2013 Sep 27. EMBO J. 2013. PMID: 24076655 Free PMC article.

2

Coupled monoubiquitylation of the co-E3 ligase DCNL1 by Ariadne-RBR E3 ubiquitin ligases promotes cullin-RING ligase complex remodeling.

Kelsall IR, Kristariyanto YA, Knebel A, Wood NT, Kulathu Y, Alpi AF. Kelsall IR, et al. J Biol Chem. 2019 Feb 22;294(8):2651-2664. doi: 10.1074/jbc.RA118.005861. Epub 2018 Dec 26. J Biol Chem. 2019. PMID: 30587576 Free PMC article.

3

HOIL-1 ubiquitin ligase activity targets unbranched glucosaccharides and is required to prevent polyglucosan accumulation.

Kelsall IR, McCrory EH, Xu Y, Scudamore CL, Nanda SK, Mancebo-Gamella P, Wood NT, Knebel A, Matthews SJ, Cohen P. Kelsall IR, et al. EMBO J. 2022 Apr 19;41(8):e109700. doi: 10.15252/embj.2021109700. Epub 2022 Mar 11. EMBO J. 2022. PMID: 35274759 Free PMC article.

4

Two Distinct Types of E3 Ligases Work in Unison to Regulate Substrate Ubiquitylation.

Scott DC, Rhee DY, Duda DM, Kelsall IR, Olszewski JL, Paulo JA, de Jong A, Ovaa H, Alpi AF, Harper JW, Schulman BA. Scott DC, et al. Among authors: kelsall ir. Cell. 2016 Aug 25;166(5):1198-1214.e24. doi: 10.1016/j.cell.2016.07.027. Cell. 2016. PMID: 27565346 Free PMC article.

5

Blocking an N-terminal acetylation-dependent protein interaction inhibits an E3 ligase.

Scott DC, Hammill JT, Min J, Rhee DY, Connelly M, Sviderskiy VO, Bhasin D, Chen Y, Ong SS, Chai SC, Goktug AN, Huang G, Monda JK, Low J, Kim HS, Paulo JA, Cannon JR, Shelat AA, Chen T, Kelsall IR, Alpi AF, Pagala V, Wang X, Peng J, Singh B, Harper JW, Schulman BA, Guy RK. Scott DC, et al. Among authors: kelsall ir. Nat Chem Biol. 2017 Aug;13(8):850-857. doi: 10.1038/nchembio.2386. Epub 2017 Jun 5. Nat Chem Biol. 2017. PMID: 28581483 Free PMC article.

6

The E3 ligase HOIL-1 catalyses ester bond formation between ubiquitin and components of the Myddosome in mammalian cells.

Kelsall IR, Zhang J, Knebel A, Arthur JSC, Cohen P. Kelsall IR, et al. Proc Natl Acad Sci U S A. 2019 Jul 2;116(27):13293-13298. doi: 10.1073/pnas.1905873116. Epub 2019 Jun 17. Proc Natl Acad Sci U S A. 2019. PMID: 31209050 Free PMC article.

7

The Fanconi anaemia components UBE2T and FANCM are functionally linked to nucleotide excision repair.

Kelsall IR, Langenick J, MacKay C, Patel KJ, Alpi AF. Kelsall IR, et al. PLoS One. 2012;7(5):e36970. doi: 10.1371/journal.pone.0036970. Epub 2012 May 15. PLoS One. 2012. PMID: 22615860 Free PMC article.

8

Roles of the TRAF6 and Pellino E3 ligases in MyD88 and RANKL signaling.

Strickson S, Emmerich CH, Goh ETH, Zhang J, Kelsall IR, Macartney T, Hastie CJ, Knebel A, Peggie M, Marchesi F, Arthur JSC, Cohen P. Strickson S, et al. Among authors: kelsall ir. Proc Natl Acad Sci U S A. 2017 Apr 25;114(17):E3481-E3489. doi: 10.1073/pnas.1702367114. Epub 2017 Apr 12. Proc Natl Acad Sci U S A. 2017. PMID: 28404732 Free PMC article.

9

HOIL-1, an atypical E3 ligase that controls MyD88 signalling by forming ester bonds between ubiquitin and components of the Myddosome.

Cohen P, Kelsall IR, Nanda SK, Zhang J. Cohen P, et al. Among authors: kelsall ir. Adv Biol Regul. 2020 Jan;75:100666. doi: 10.1016/j.jbior.2019.100666. Epub 2019 Oct 5. Adv Biol Regul. 2020. PMID: 31615747 Free PMC article. Review.

10

Ppm1E is an in cellulo AMP-activated protein kinase phosphatase.

Voss M, Paterson J, Kelsall IR, Martín-Granados C, Hastie CJ, Peggie MW, Cohen PT. Voss M, et al. Among authors: kelsall ir. Cell Signal. 2011 Jan;23(1):114-24. doi: 10.1016/j.cellsig.2010.08.010. Epub 2010 Aug 27. Cell Signal. 2011. PMID: 20801214

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