Haigis KM - Search Results

1

Network analysis of differential Ras isoform mutation effects on intestinal epithelial responses to TNF-α.

Lau KS, Schrier SB, Gierut J, Lyons J, Lauffenburger DA, Haigis KM. Lau KS, et al. Among authors: haigis km. Integr Biol (Camb). 2013 Nov;5(11):1355-65. doi: 10.1039/c3ib40062j. Epub 2013 Oct 2. Integr Biol (Camb). 2013. PMID: 24084984 Free PMC article.

2

Rare germline structural variants increase risk for pediatric solid tumors.

Gillani R, Collins RL, Crowdis J, Garza A, Jones JK, Walker M, Sanchis-Juan A, Whelan C, Pierce-Hoffman E, Talkowski M, Brand H, Haigis K, LoPiccolo J, AlDubayan SH, Gusev A, Crompton BD, Janeway KA, Van Allen EM. Gillani R, et al. bioRxiv [Preprint]. 2024 Apr 29:2024.04.27.591484. doi: 10.1101/2024.04.27.591484. bioRxiv. 2024. PMID: 38746320 Free PMC article. Preprint.

3

Allosteric Regulation of Switch-II Domain Controls KRAS Oncogenicity.

Yang MH, Tran TH, Hunt B, Agnor R, Johnson CW, Shui B, Waybright TJ, Nowak JA, Stephen AG, Simanshu DK, Haigis KM. Yang MH, et al. Among authors: haigis km. Cancer Res. 2023 Oct 2;83(19):3176-3183. doi: 10.1158/0008-5472.CAN-22-3210. Cancer Res. 2023. PMID: 37556505 Free PMC article.

4

Genomic analysis of early-stage lung cancer reveals a role for TP53 mutations in distant metastasis.

Van Egeren D, Kohli K, Warner JL, Bedard PL, Riely G, Lepisto E, Schrag D, LeNoue-Newton M, Catalano P, Kehl KL, Michor F; AACR Project GENIE Consortium represented by Shawn Sweeney. Van Egeren D, et al. Sci Rep. 2022 Nov 9;12(1):19055. doi: 10.1038/s41598-022-21448-1. Sci Rep. 2022. PMID: 36351964 Free PMC article.

5

Differential effects of oncogenic K-Ras and N-Ras on proliferation, differentiation and tumor progression in the colon.

Haigis KM, Kendall KR, Wang Y, Cheung A, Haigis MC, Glickman JN, Niwa-Kawakita M, Sweet-Cordero A, Sebolt-Leopold J, Shannon KM, Settleman J, Giovannini M, Jacks T. Haigis KM, et al. Among authors: haigis mc. Nat Genet. 2008 May;40(5):600-8. doi: 10.1038/ng.115. Epub 2008 Mar 30. Nat Genet. 2008. PMID: 18372904 Free PMC article.

6

RAS mutations affect tumor necrosis factor-induced apoptosis in colon carcinoma cells via ERK-modulatory negative and positive feedback circuits along with non-ERK pathway effects.

Kreeger PK, Mandhana R, Alford SK, Haigis KM, Lauffenburger DA. Kreeger PK, et al. Among authors: haigis km. Cancer Res. 2009 Oct 15;69(20):8191-9. doi: 10.1158/0008-5472.CAN-09-1921. Epub 2009 Sep 29. Cancer Res. 2009. PMID: 19789336 Free PMC article.

7

Non-redundancy within the RAS oncogene family: insights into mutational disparities in cancer.

Lau KS, Haigis KM. Lau KS, et al. Among authors: haigis km. Mol Cells. 2009 Oct 31;28(4):315-20. doi: 10.1007/s10059-009-0143-7. Epub 2009 Sep 30. Mol Cells. 2009. PMID: 19812895 Free PMC article. Review.

8

Integration of multiple signaling pathway activities resolves K-RAS/N-RAS mutation paradox in colon epithelial cell response to inflammatory cytokine stimulation.

Kreeger PK, Wang Y, Haigis KM, Lauffenburger DA. Kreeger PK, et al. Among authors: haigis km. Integr Biol (Camb). 2010 Apr;2(4):202-8. doi: 10.1039/b925935j. Epub 2010 Mar 8. Integr Biol (Camb). 2010. PMID: 20473400 Free PMC article.

9

In vivo systems analysis identifies spatial and temporal aspects of the modulation of TNF-α-induced apoptosis and proliferation by MAPKs.

Lau KS, Juchheim AM, Cavaliere KR, Philips SR, Lauffenburger DA, Haigis KM. Lau KS, et al. Among authors: haigis km. Sci Signal. 2011 Mar 22;4(165):ra16. doi: 10.1126/scisignal.2001338. Sci Signal. 2011. PMID: 21427409 Free PMC article.

10

Regulation of homeostasis and oncogenesis in the intestinal epithelium by Ras.

Velho S, Haigis KM. Velho S, et al. Among authors: haigis km. Exp Cell Res. 2011 Nov 15;317(19):2732-9. doi: 10.1016/j.yexcr.2011.06.002. Epub 2011 Jun 17. Exp Cell Res. 2011. PMID: 21741971 Free PMC article. Review.

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