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Novel methylation biomarker panel for the early detection of pancreatic cancer.
Yi JM, Guzzetta AA, Bailey VJ, Downing SR, Van Neste L, Chiappinelli KB, Keeley BP, Stark A, Herrera A, Wolfgang C, Pappou EP, Iacobuzio-Donahue CA, Goggins MG, Herman JG, Wang TH, Baylin SB, Ahuja N. Yi JM, et al. Among authors: pappou ep. Clin Cancer Res. 2013 Dec 1;19(23):6544-6555. doi: 10.1158/1078-0432.CCR-12-3224. Epub 2013 Oct 2. Clin Cancer Res. 2013. PMID: 24088737 Free PMC article.
Transient low doses of DNA-demethylating agents exert durable antitumor effects on hematological and epithelial tumor cells.
Tsai HC, Li H, Van Neste L, Cai Y, Robert C, Rassool FV, Shin JJ, Harbom KM, Beaty R, Pappou E, Harris J, Yen RW, Ahuja N, Brock MV, Stearns V, Feller-Kopman D, Yarmus LB, Lin YC, Welm AL, Issa JP, Minn I, Matsui W, Jang YY, Sharkis SJ, Baylin SB, Zahnow CA. Tsai HC, et al. Cancer Cell. 2012 Mar 20;21(3):430-46. doi: 10.1016/j.ccr.2011.12.029. Cancer Cell. 2012. PMID: 22439938 Free PMC article.
CpG island methylator phenotype-positive tumors in the absence of MLH1 methylation constitute a distinct subset of duodenal adenocarcinomas and are associated with poor prognosis.
Fu T, Pappou EP, Guzzetta AA, Jeschke J, Kwak R, Dave P, Hooker CM, Morgan R, Baylin SB, Iacobuzio-Donahue CA, Wolfgang CL, Ahuja N. Fu T, et al. Among authors: pappou ep. Clin Cancer Res. 2012 Sep 1;18(17):4743-52. doi: 10.1158/1078-0432.CCR-12-0707. Epub 2012 Jul 23. Clin Cancer Res. 2012. PMID: 22825585 Free PMC article.
Epigenetic silencing of neurofilament genes promotes an aggressive phenotype in breast cancer.
Calmon MF, Jeschke J, Zhang W, Dhir M, Siebenkäs C, Herrera A, Tsai HC, O'Hagan HM, Pappou EP, Hooker CM, Fu T, Schuebel KE, Gabrielson E, Rahal P, Herman JG, Baylin SB, Ahuja N. Calmon MF, et al. Among authors: pappou ep. Epigenetics. 2015;10(7):622-32. doi: 10.1080/15592294.2015.1050173. Epigenetics. 2015. PMID: 25985363 Free PMC article.
78 results