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Loss of the TGFβ-activating integrin αvβ8 on dendritic cells protects mice from chronic intestinal parasitic infection via control of type 2 immunity.
Worthington JJ, Klementowicz JE, Rahman S, Czajkowska BI, Smedley C, Waldmann H, Sparwasser T, Grencis RK, Travis MA. Worthington JJ, et al. Among authors: sparwasser t. PLoS Pathog. 2013;9(10):e1003675. doi: 10.1371/journal.ppat.1003675. Epub 2013 Oct 3. PLoS Pathog. 2013. PMID: 24098124 Free PMC article.
TGFβ-activation by dendritic cells drives Th17 induction and intestinal contractility and augments the expulsion of the parasite Trichinella spiralis in mice.
Steel N, Faniyi AA, Rahman S, Swietlik S, Czajkowska BI, Chan BT, Hardgrave A, Steel A, Sparwasser TD, Assas MB, Grencis RK, Travis MA, Worthington JJ. Steel N, et al. Among authors: sparwasser td. PLoS Pathog. 2019 Apr 18;15(4):e1007657. doi: 10.1371/journal.ppat.1007657. eCollection 2019 Apr. PLoS Pathog. 2019. PMID: 30998782 Free PMC article.
Correction: TGFβ-activation by dendritic cells drives Th17 induction and intestinal contractility and augments the expulsion of the parasite Trichinella spiralis in mice.
Steel N, Faniyi AA, Rahman S, Swietlik S, Czajkowska BI, Chan BT, Hardgrave A, Steel A, Sparwasser TD, Assas MB, Grencis RK, Travis MA, Worthington JJ. Steel N, et al. Among authors: sparwasser td. PLoS Pathog. 2021 Nov 10;17(11):e1010063. doi: 10.1371/journal.ppat.1010063. eCollection 2021 Nov. PLoS Pathog. 2021. PMID: 34758039 Free PMC article.
Absence of Siglec-H in MCMV infection elevates interferon alpha production but does not enhance viral clearance.
Puttur F, Arnold-Schrauf C, Lahl K, Solmaz G, Lindenberg M, Mayer CT, Gohmert M, Swallow M, van Helt C, Schmitt H, Nitschke L, Lambrecht BN, Lang R, Messerle M, Sparwasser T. Puttur F, et al. Among authors: sparwasser t. PLoS Pathog. 2013;9(9):e1003648. doi: 10.1371/journal.ppat.1003648. Epub 2013 Sep 26. PLoS Pathog. 2013. PMID: 24086137 Free PMC article.
Foxp3⁺ regulatory T cells delay expulsion of intestinal nematodes by suppression of IL-9-driven mast cell activation in BALB/c but not in C57BL/6 mice.
Blankenhaus B, Reitz M, Brenz Y, Eschbach ML, Hartmann W, Haben I, Sparwasser T, Huehn J, Kühl A, Feyerabend TB, Rodewald HR, Breloer M. Blankenhaus B, et al. Among authors: sparwasser t. PLoS Pathog. 2014 Feb 6;10(2):e1003913. doi: 10.1371/journal.ppat.1003913. eCollection 2014 Feb. PLoS Pathog. 2014. PMID: 24516385 Free PMC article.
TLR4 abrogates the Th1 immune response through IRF1 and IFN-β to prevent immunopathology during L. infantum infection.
Sacramento LA, Benevides L, Maruyama SR, Tavares L, Fukutani KF, Francozo M, Sparwasser T, Cunha FQ, Almeida RP, da Silva JS, Carregaro V. Sacramento LA, et al. Among authors: sparwasser t. PLoS Pathog. 2020 Mar 25;16(3):e1008435. doi: 10.1371/journal.ppat.1008435. eCollection 2020 Mar. PLoS Pathog. 2020. PMID: 32210480 Free PMC article.
Conventional bone marrow-derived dendritic cells contribute to toll-like receptor-independent production of alpha/beta interferon in response to inactivated parapoxvirus ovis.
Siegemund S, Hartl A, von Buttlar H, Dautel F, Raue R, Freudenberg MA, Fejer G, Büttner M, Köhler G, Kirschning CJ, Sparwasser T, Alber G. Siegemund S, et al. Among authors: sparwasser t. J Virol. 2009 Sep;83(18):9411-22. doi: 10.1128/JVI.02362-08. Epub 2009 Jul 1. J Virol. 2009. PMID: 19570869 Free PMC article.
236 results