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Nicotinamide phosphoribosyltransferase inhibition reduces intraplaque CXCL1 production and associated neutrophil infiltration in atherosclerotic mice.
Nencioni A, da Silva RF, Fraga-Silva RA, Steffens S, Fabre M, Bauer I, Caffa I, Magnone M, Sociali G, Quercioli A, Pelli G, Lenglet S, Galan K, Burger F, Vázquez Calvo S, Bertolotto M, Bruzzone S, Ballestrero A, Patrone F, Dallegri F, Santos RA, Stergiopulos N, Mach F, Vuilleumier N, Montecucco F. Nencioni A, et al. Among authors: dallegri f. Thromb Haemost. 2014 Feb;111(2):308-22. doi: 10.1160/TH13-07-0531. Epub 2013 Nov 7. Thromb Haemost. 2014. PMID: 24196571 Free article.
Anti-apoA-1 auto-antibodies increase mouse atherosclerotic plaque vulnerability, myocardial necrosis and mortality triggering TLR2 and TLR4.
Montecucco F, Braunersreuther V, Burger F, Lenglet S, Pelli G, Carbone F, Fraga-Silva R, Stergiopulos N, Monaco C, Mueller C, Pagano S, Dallegri F, Mach F, Vuilleumier N. Montecucco F, et al. Among authors: dallegri f. Thromb Haemost. 2015 Aug;114(2):410-22. doi: 10.1160/TH14-12-1039. Epub 2015 Apr 16. Thromb Haemost. 2015. PMID: 25879306
The activation of the cannabinoid receptor type 2 reduces neutrophilic protease-mediated vulnerability in atherosclerotic plaques.
Montecucco F, Di Marzo V, da Silva RF, Vuilleumier N, Capettini L, Lenglet S, Pagano S, Piscitelli F, Quintao S, Bertolotto M, Pelli G, Galan K, Pilet L, Kuzmanovic K, Burger F, Pane B, Spinella G, Braunersreuther V, Gayet-Ageron A, Pende A, Viviani GL, Palombo D, Dallegri F, Roux-Lombard P, Santos RA, Stergiopulos N, Steffens S, Mach F. Montecucco F, et al. Among authors: dallegri f. Eur Heart J. 2012 Apr;33(7):846-56. doi: 10.1093/eurheartj/ehr449. Epub 2011 Nov 22. Eur Heart J. 2012. PMID: 22112961 Free PMC article.
Receptor activator of NF- κB ligand (RANKL) increases the release of neutrophil products associated with coronary vulnerability.
Quercioli A, Mach F, Bertolotto M, Lenglet S, Vuilleumier N, Galan K, Pagano S, Braunersreuther V, Pelli G, Pistoia V, Bianchi G, Cittadini G, Viviani GL, Pende A, Roux-Lombard P, Thomas A, Staub C, Ratib O, Dallegri F, Schindler TH, Montecucco F. Quercioli A, et al. Among authors: dallegri f. Thromb Haemost. 2012 Jan;107(1):124-39. doi: 10.1160/TH11-05-0324. Epub 2011 Nov 24. Thromb Haemost. 2012. PMID: 22116393
Inhibition of nicotinamide phosphoribosyltransferase reduces neutrophil-mediated injury in myocardial infarction.
Montecucco F, Bauer I, Braunersreuther V, Bruzzone S, Akhmedov A, Lüscher TF, Speer T, Poggi A, Mannino E, Pelli G, Galan K, Bertolotto M, Lenglet S, Garuti A, Montessuit C, Lerch R, Pellieux C, Vuilleumier N, Dallegri F, Mage J, Sebastian C, Mostoslavsky R, Gayet-Ageron A, Patrone F, Mach F, Nencioni A. Montecucco F, et al. Among authors: dallegri f. Antioxid Redox Signal. 2013 Feb 20;18(6):630-41. doi: 10.1089/ars.2011.4487. Epub 2012 May 14. Antioxid Redox Signal. 2013. PMID: 22452634 Free PMC article.
Treatment with Evasin-3 reduces atherosclerotic vulnerability for ischemic stroke, but not brain injury in mice.
Copin JC, da Silva RF, Fraga-Silva RA, Capettini L, Quintao S, Lenglet S, Pelli G, Galan K, Burger F, Braunersreuther V, Schaller K, Deruaz M, Proudfoot AE, Dallegri F, Stergiopulos N, Santos RA, Gasche Y, Mach F, Montecucco F. Copin JC, et al. Among authors: dallegri f. J Cereb Blood Flow Metab. 2013 Apr;33(4):490-8. doi: 10.1038/jcbfm.2012.198. Epub 2012 Dec 19. J Cereb Blood Flow Metab. 2013. PMID: 23250107 Free PMC article.
Treatment with Angiotensin-(1-7) reduces inflammation in carotid atherosclerotic plaques.
Fraga-Silva RA, Savergnini SQ, Montecucco F, Nencioni A, Caffa I, Soncini D, Costa-Fraga FP, De Sousa FB, Sinisterra RD, Capettini LA, Lenglet S, Galan K, Pelli G, Bertolotto M, Pende A, Spinella G, Pane B, Dallegri F, Palombo D, Mach F, Stergiopulos N, Santos RA, da Silva RF. Fraga-Silva RA, et al. Among authors: dallegri f. Thromb Haemost. 2014 Apr 1;111(4):736-47. doi: 10.1160/TH13-06-0448. Epub 2014 Feb 6. Thromb Haemost. 2014. PMID: 24499778
Treatment with sulphated galactan inhibits macrophage chemotaxis and reduces intraplaque macrophage content in atherosclerotic mice.
Gomes Quinderé AL, Barros Benevides NM, Pelli G, Lenglet S, Burger F, Carbone F, Fraga-Silva RA, Stergiopulos N, Pagano S, Bertolotto M, Dallegri F, Vuilleumier N, Mach F, Montecucco F. Gomes Quinderé AL, et al. Among authors: dallegri f. Vascul Pharmacol. 2015 Aug;71:84-92. doi: 10.1016/j.vph.2015.02.015. Epub 2015 Apr 10. Vascul Pharmacol. 2015. PMID: 25869506
Anti-apolipoprotein A-1 auto-antibodies as active modulators of atherothrombosis.
Pagano S, Carbone F, Burger F, Roth A, Bertolotto M, Pane B, Spinella G, Palombo D, Pende A, Dallegri F, Satta N, Virzi J, Fontana P, Mach F, Montecucco F, Vuilleumier N. Pagano S, et al. Among authors: dallegri f. Thromb Haemost. 2016 Aug 30;116(3):554-64. doi: 10.1160/TH16-03-0229. Epub 2016 Jun 30. Thromb Haemost. 2016. PMID: 27356567
277 results