Vondenhoff GH - Search Results

1

N-alkylated aminoacyl sulfamoyladenosines as potential inhibitors of aminoacylation reactions and microcin C analogues containing D-amino acids.

Vondenhoff GH, Pugach K, Gadakh B, Carlier L, Rozenski J, Froeyen M, Severinov K, Van Aerschot A. Vondenhoff GH, et al. PLoS One. 2013 Nov 4;8(11):e79234. doi: 10.1371/journal.pone.0079234. eCollection 2013. PLoS One. 2013. PMID: 24223911 Free PMC article.

2

Base substituted 5'-O-(N-isoleucyl)sulfamoyl nucleoside analogues as potential antibacterial agents.

Gadakh B, Vondenhoff G, Lescrinier E, Rozenski J, Froeyen M, Van Aerschot A. Gadakh B, et al. Bioorg Med Chem. 2014 May 15;22(10):2875-86. doi: 10.1016/j.bmc.2014.03.040. Epub 2014 Apr 5. Bioorg Med Chem. 2014. PMID: 24746466

3

Characterization of peptide chain length and constituency requirements for YejABEF-mediated uptake of microcin C analogues.

Vondenhoff GH, Blanchaert B, Geboers S, Kazakov T, Datsenko KA, Wanner BL, Rozenski J, Severinov K, Van Aerschot A. Vondenhoff GH, et al. J Bacteriol. 2011 Jul;193(14):3618-23. doi: 10.1128/JB.00172-11. Epub 2011 May 20. J Bacteriol. 2011. PMID: 21602342 Free PMC article.

4

Extended targeting potential and improved synthesis of Microcin C analogs as antibacterials.

Vondenhoff GH, Dubiley S, Severinov K, Lescrinier E, Rozenski J, Van Aerschot A. Vondenhoff GH, et al. Bioorg Med Chem. 2011 Sep 15;19(18):5462-7. doi: 10.1016/j.bmc.2011.07.052. Epub 2011 Aug 3. Bioorg Med Chem. 2011. PMID: 21855353

5

Microcin C: biosynthesis, mode of action, and potential as a lead in antibiotics development.

Vondenhoff GH, Van Aerschot A. Vondenhoff GH, et al. Nucleosides Nucleotides Nucleic Acids. 2011 Jul-Aug;30(7-8):465-74. doi: 10.1080/15257770.2011.583972. Nucleosides Nucleotides Nucleic Acids. 2011. PMID: 21888539

6

Aminoacyl-tRNA synthetase inhibitors as potential antibiotics.

Vondenhoff GH, Van Aerschot A. Vondenhoff GH, et al. Eur J Med Chem. 2011 Nov;46(11):5227-36. doi: 10.1016/j.ejmech.2011.08.049. Epub 2011 Sep 16. Eur J Med Chem. 2011. PMID: 21968372 Review.

7

Antibacterial 5'-O-(N-dipeptidyl)-sulfamoyladenosines.

Van de Vijver P, Vondenhoff GH, Denivelle S, Rozenski J, Verhaegen J, Van Aerschot A, Herdewijn P. Van de Vijver P, et al. Among authors: vondenhoff gh. Bioorg Med Chem. 2009 Jan 1;17(1):260-9. doi: 10.1016/j.bmc.2008.11.054. Epub 2008 Nov 27. Bioorg Med Chem. 2009. PMID: 19070499

8

Microcin C and albomycin analogues with aryl-tetrazole substituents as nucleobase isosters are selective inhibitors of bacterial aminoacyl tRNA synthetases but lack efficient uptake.

Vondenhoff GH, Gadakh B, Severinov K, Van Aerschot A. Vondenhoff GH, et al. Chembiochem. 2012 Sep 3;13(13):1959-69. doi: 10.1002/cbic.201200174. Epub 2012 Jul 30. Chembiochem. 2012. PMID: 22847961

9

Synthesis and structural insights into the binding mode of the albomycin δ1 core and its analogues in complex with their target aminoacyl-tRNA synthetase.

Gadakh B, Vondenhoff G, Pang L, Nautiyal M, De Graef S, Strelkov SV, Weeks SD, Van Aerschot A. Gadakh B, et al. Bioorg Med Chem. 2020 Sep 1;28(17):115645. doi: 10.1016/j.bmc.2020.115645. Epub 2020 Jul 13. Bioorg Med Chem. 2020. PMID: 32773091

10

Synthetic microcin C analogs targeting different aminoacyl-tRNA synthetases.

Van de Vijver P, Vondenhoff GH, Kazakov TS, Semenova E, Kuznedelov K, Metlitskaya A, Van Aerschot A, Severinov K. Van de Vijver P, et al. Among authors: vondenhoff gh. J Bacteriol. 2009 Oct;191(20):6273-80. doi: 10.1128/JB.00829-09. Epub 2009 Aug 14. J Bacteriol. 2009. PMID: 19684138 Free PMC article.

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