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Blocking lactate export by inhibiting the Myc target MCT1 Disables glycolysis and glutathione synthesis.
Doherty JR, Yang C, Scott KE, Cameron MD, Fallahi M, Li W, Hall MA, Amelio AL, Mishra JK, Li F, Tortosa M, Genau HM, Rounbehler RJ, Lu Y, Dang CV, Kumar KG, Butler AA, Bannister TD, Hooper AT, Unsal-Kacmaz K, Roush WR, Cleveland JL. Doherty JR, et al. Among authors: butler aa. Cancer Res. 2014 Feb 1;74(3):908-20. doi: 10.1158/0008-5472.CAN-13-2034. Epub 2013 Nov 27. Cancer Res. 2014. PMID: 24285728 Free PMC article.
Identification of SR3335 (ML-176): a synthetic RORα selective inverse agonist.
Kumar N, Kojetin DJ, Solt LA, Kumar KG, Nuhant P, Duckett DR, Cameron MD, Butler AA, Roush WR, Griffin PR, Burris TP. Kumar N, et al. Among authors: butler aa. ACS Chem Biol. 2011 Mar 18;6(3):218-22. doi: 10.1021/cb1002762. Epub 2010 Dec 6. ACS Chem Biol. 2011. PMID: 21090593 Free PMC article.
Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists.
Solt LA, Wang Y, Banerjee S, Hughes T, Kojetin DJ, Lundasen T, Shin Y, Liu J, Cameron MD, Noel R, Yoo SH, Takahashi JS, Butler AA, Kamenecka TM, Burris TP. Solt LA, et al. Among authors: butler aa. Nature. 2012 Mar 29;485(7396):62-8. doi: 10.1038/nature11030. Nature. 2012. PMID: 22460951 Free PMC article.
Hepatocyte expression of the micropeptide adropin regulates the liver fasting response and is enhanced by caloric restriction.
Banerjee S, Ghoshal S, Stevens JR, McCommis KS, Gao S, Castro-Sepulveda M, Mizgier ML, Girardet C, Kumar KG, Galgani JE, Niehoff ML, Farr SA, Zhang J, Butler AA. Banerjee S, et al. Among authors: butler aa. J Biol Chem. 2020 Oct 2;295(40):13753-13768. doi: 10.1074/jbc.RA120.014381. Epub 2020 Jul 29. J Biol Chem. 2020. PMID: 32727846 Free PMC article.
Obesity accelerates thymic aging.
Yang H, Youm YH, Vandanmagsar B, Rood J, Kumar KG, Butler AA, Dixit VD. Yang H, et al. Among authors: butler aa. Blood. 2009 Oct 29;114(18):3803-12. doi: 10.1182/blood-2009-03-213595. Epub 2009 Aug 31. Blood. 2009. PMID: 19721009 Free PMC article.
Genetic dissection of the functions of the melanocortin-3 receptor, a seven-transmembrane G-protein-coupled receptor, suggests roles for central and peripheral receptors in energy homeostasis.
Begriche K, Levasseur PR, Zhang J, Rossi J, Skorupa D, Solt LA, Young B, Burris TP, Marks DL, Mynatt RL, Butler AA. Begriche K, et al. Among authors: butler aa. J Biol Chem. 2011 Nov 25;286(47):40771-81. doi: 10.1074/jbc.M111.278374. Epub 2011 Oct 7. J Biol Chem. 2011. PMID: 21984834 Free PMC article.
Melanocortin-3 receptors and metabolic homeostasis.
Begriche K, Girardet C, McDonald P, Butler AA. Begriche K, et al. Among authors: butler aa. Prog Mol Biol Transl Sci. 2013;114:109-46. doi: 10.1016/B978-0-12-386933-3.00004-2. Prog Mol Biol Transl Sci. 2013. PMID: 23317784 Free PMC article. Review.
145 results