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Pilot trial of EZN-2968, an antisense oligonucleotide inhibitor of hypoxia-inducible factor-1 alpha (HIF-1α), in patients with refractory solid tumors.
Jeong W, Rapisarda A, Park SR, Kinders RJ, Chen A, Melillo G, Turkbey B, Steinberg SM, Choyke P, Doroshow JH, Kummar S. Jeong W, et al. Among authors: chen a. Cancer Chemother Pharmacol. 2014 Feb;73(2):343-8. doi: 10.1007/s00280-013-2362-z. Epub 2013 Nov 30. Cancer Chemother Pharmacol. 2014. PMID: 24292632 Free PMC article. Clinical Trial.
Phase I clinical trial of continuous infusion cyclopentenyl cytosine.
Politi PM, Xie F, Dahut W, Ford H Jr, Kelley JA, Bastian A, Setser A, Allegra CJ, Chen AP, Hamilton JM, et al. Politi PM, et al. Among authors: chen ap. Cancer Chemother Pharmacol. 1995;36(6):513-23. doi: 10.1007/BF00685802. Cancer Chemother Pharmacol. 1995. PMID: 7554044 Clinical Trial.
Phase I and pharmacokinetic study of recombinant human granulocyte-macrophage colony-stimulating factor given in combination with fluorouracil plus calcium leucovorin in metastatic gastrointestinal adenocarcinoma.
Grem JL, McAtee N, Murphy RF, Hamilton JM, Balis F, Steinberg S, Arbuck SG, Setser A, Jordan E, Chen A, et al. Grem JL, et al. Among authors: chen a. J Clin Oncol. 1994 Mar;12(3):560-8. doi: 10.1200/JCO.1994.12.3.560. J Clin Oncol. 1994. PMID: 8120554 Clinical Trial.
A pilot study of interferon alpha-2a, fluorouracil, and leucovorin given with granulocyte-macrophage colony stimulating factor in advanced gastrointestinal adenocarcinoma.
Shapiro JD, Harold N, Takimoto C, Hamilton JM, Vaughn D, Chen A, Steinberg SM, Liewehr D, Allegra C, Monahan B, Lash A, Grollman F, Flemming D, Behan K, Johnston PG, Haller D, Quinn M, Morrison G, Grem JL. Shapiro JD, et al. Among authors: chen a. Clin Cancer Res. 1999 Sep;5(9):2399-408. Clin Cancer Res. 1999. PMID: 10499610 Clinical Trial.
A phase I and pharmacologic study of 9-aminocamptothecin administered as a 120-h infusion weekly to adult cancer patients.
Thomas RR, Dahut W, Harold N, Grem JL, Monahan BP, Liang M, Band RA, Cottrell J, Llorens V, Smith JA, Corse W, Arbuck SG, Wright J, Chen AP, Shapiro JD, Hamilton JM, Allegra CJ, Takimoto CH. Thomas RR, et al. Among authors: chen ap. Cancer Chemother Pharmacol. 2001 Sep;48(3):215-22. doi: 10.1007/s002800100329. Cancer Chemother Pharmacol. 2001. PMID: 11592343 Clinical Trial.
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