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The synthesis and structure revision of NSC-134754.
Hickin JA, Ahmed A, Fucke K, Ashcroft M, Jones K. Hickin JA, et al. Among authors: ashcroft m. Chem Commun (Camb). 2014 Feb 7;50(10):1238-40. doi: 10.1039/c3cc48189a. Chem Commun (Camb). 2014. PMID: 24336320
Small-molecule activation of p53 blocks hypoxia-inducible factor 1alpha and vascular endothelial growth factor expression in vivo and leads to tumor cell apoptosis in normoxia and hypoxia.
Yang J, Ahmed A, Poon E, Perusinghe N, de Haven Brandon A, Box G, Valenti M, Eccles S, Rouschop K, Wouters B, Ashcroft M. Yang J, et al. Among authors: ashcroft m. Mol Cell Biol. 2009 Apr;29(8):2243-53. doi: 10.1128/MCB.00959-08. Epub 2009 Feb 17. Mol Cell Biol. 2009. PMID: 19223463 Free PMC article.
TRP-ing off the p53 apoptotic switch.
Ahmed A, Ashcroft M. Ahmed A, et al. Among authors: ashcroft m. Pigment Cell Melanoma Res. 2010 Jul 29. doi: 10.1111/j.1755-1471.2010.00746.x. Online ahead of print. Pigment Cell Melanoma Res. 2010. PMID: 20673277 No abstract available.
TRP-ing off the p53 apoptotic switch.
Ahmed A, Ashcroft M. Ahmed A, et al. Among authors: ashcroft m. Pigment Cell Melanoma Res. 2010 Oct;23(5):581-2. doi: 10.1111/j.1755-148X.2010.00747.x. Pigment Cell Melanoma Res. 2010. PMID: 20840120 No abstract available.
Activation of a unique p53-dependent DNA damage response.
Yang J, Ahmed A, Ashcroft M. Yang J, et al. Among authors: ashcroft m. Cell Cycle. 2009 May 15;8(10):1630-2. doi: 10.4161/cc.8.10.8326. Epub 2009 May 2. Cell Cycle. 2009. PMID: 19372763 No abstract available.
188 results