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Combined inhibitor free-energy landscape and structural analysis reports on the mannosidase conformational coordinate.
Williams RJ, Iglesias-Fernández J, Stepper J, Jackson A, Thompson AJ, Lowe EC, White JM, Gilbert HJ, Rovira C, Davies GJ, Williams SJ. Williams RJ, et al. Among authors: lowe ec. Angew Chem Int Ed Engl. 2014 Jan 20;53(4):1087-91. doi: 10.1002/anie.201308334. Epub 2013 Dec 11. Angew Chem Int Ed Engl. 2014. PMID: 24339341 Free PMC article.
Human gut Bacteroidetes can utilize yeast mannan through a selfish mechanism.
Cuskin F, Lowe EC, Temple MJ, Zhu Y, Cameron E, Pudlo NA, Porter NT, Urs K, Thompson AJ, Cartmell A, Rogowski A, Hamilton BS, Chen R, Tolbert TJ, Piens K, Bracke D, Vervecken W, Hakki Z, Speciale G, Munōz-Munōz JL, Day A, Peña MJ, McLean R, Suits MD, Boraston AB, Atherly T, Ziemer CJ, Williams SJ, Davies GJ, Abbott DW, Martens EC, Gilbert HJ. Cuskin F, et al. Among authors: lowe ec. Nature. 2015 Jan 8;517(7533):165-169. doi: 10.1038/nature13995. Nature. 2015. PMID: 25567280 Free PMC article.
Corrigendum: Human gut Bacteroidetes can utilize yeast mannan through a selfish mechanism.
Cuskin F, Lowe EC, Temple MJ, Zhu Y, Cameron EA, Pudlo NA, Porter NT, Urs K, Thompson AJ, Cartmell A, Rogowski A, Hamilton BS, Chen R, Tolbert TJ, Piens K, Bracke D, Vervecken W, Hakki Z, Speciale G, Munōz-Munōz JL, Day A, Peña MJ, McLean R, Suits MD, Boraston AB, Atherly T, Ziemer CJ, Williams SJ, Davies GJ, Abbott DW, Martens EC, Gilbert HJ. Cuskin F, et al. Among authors: lowe ec. Nature. 2015 Apr 16;520(7547):388. doi: 10.1038/nature14334. Epub 2015 Mar 4. Nature. 2015. PMID: 25739504 No abstract available.
A surface endogalactanase in Bacteroides thetaiotaomicron confers keystone status for arabinogalactan degradation.
Cartmell A, Muñoz-Muñoz J, Briggs JA, Ndeh DA, Lowe EC, Baslé A, Terrapon N, Stott K, Heunis T, Gray J, Yu L, Dupree P, Fernandes PZ, Shah S, Williams SJ, Labourel A, Trost M, Henrissat B, Gilbert HJ. Cartmell A, et al. Among authors: lowe ec. Nat Microbiol. 2018 Nov;3(11):1314-1326. doi: 10.1038/s41564-018-0258-8. Epub 2018 Oct 22. Nat Microbiol. 2018. PMID: 30349080 Free PMC article.
Author Correction: A surface endogalactanase in Bacteroides thetaiotaomicron confers keystone status for arabinogalactan degradation.
Cartmell A, Muñoz-Muñoz J, Briggs JA, Ndeh DA, Lowe EC, Baslé A, Terrapon N, Stott K, Heunis T, Gray J, Yu L, Dupree P, Fernandes PZ, Shah S, Williams SJ, Labourel A, Trost M, Henrissat B, Gilbert HJ. Cartmell A, et al. Among authors: lowe ec. Nat Microbiol. 2019 Nov;4(11):2021-2023. doi: 10.1038/s41564-019-0584-5. Nat Microbiol. 2019. PMID: 31541200
Identification of D-arabinan-degrading enzymes in mycobacteria.
Al-Jourani O, Benedict ST, Ross J, Layton AJ, van der Peet P, Marando VM, Bailey NP, Heunis T, Manion J, Mensitieri F, Franklin A, Abellon-Ruiz J, Oram SL, Parsons L, Cartmell A, Wright GSA, Baslé A, Trost M, Henrissat B, Munoz-Munoz J, Hirt RP, Kiessling LL, Lovering AL, Williams SJ, Lowe EC, Moynihan PJ. Al-Jourani O, et al. Among authors: lowe ec. Nat Commun. 2023 Apr 19;14(1):2233. doi: 10.1038/s41467-023-37839-5. Nat Commun. 2023. PMID: 37076525 Free PMC article.
The mycobacterial glycoside hydrolase LamH enables capsular arabinomannan release and stimulates growth.
Franklin A, Layton AJ, Mize T, Salgueiro VC, Sullivan R, Benedict ST, Gurcha SS, Anso I, Besra GS, Banzhaf M, Lovering AL, Williams SJ, Guerin ME, Scott NE, Prados-Rosales R, Lowe EC, Moynihan PJ. Franklin A, et al. Among authors: lowe ec. bioRxiv [Preprint]. 2023 Oct 26:2023.10.26.563968. doi: 10.1101/2023.10.26.563968. bioRxiv. 2023. PMID: 37961452 Free PMC article. Preprint.
38 results