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Methyl-substituted conformationally constrained rexinoid agonists for the retinoid X receptors demonstrate improved efficacy for cancer therapy and prevention.
Bioorg Med Chem. 2014 Jan 1;22(1):178-85. doi: 10.1016/j.bmc.2013.11.039. Epub 2013 Dec 1.
Bioorg Med Chem. 2014.
PMID: 24359708
Free PMC article.
Conformationally defined retinoic acid analogues. 5. Large-scale synthesis and mammary cancer chemopreventive activity for (2E,4E,6Z,8E)-8-(3',4'-dihydro-1'(2'H)-naphthalen-1'-ylidene)-3,7-dimethyl-2,4,6-octatrienoic acid (9cUAB30).
Atigadda VR, Vines KK, Grubbs CJ, Hill DL, Beenken SL, Bland KI, Brouillette WJ, Muccio DD.
Atigadda VR, et al. Among authors: vines kk.
J Med Chem. 2003 Aug 14;46(17):3766-9. doi: 10.1021/jm030095q.
J Med Chem. 2003.
PMID: 12904083
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9cUAB30, an RXR specific retinoid, and/or tamoxifen in the prevention of methylnitrosourea-induced mammary cancers.
Grubbs CJ, Hill DL, Bland KI, Beenken SW, Lin TH, Eto I, Atigadda VR, Vines KK, Brouillette WJ, Muccio DD.
Grubbs CJ, et al. Among authors: vines kk.
Cancer Lett. 2003 Nov 10;201(1):17-24. doi: 10.1016/s0304-3835(03)00461-0.
Cancer Lett. 2003.
PMID: 14580682
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Total syntheses of epothilones B and d.
Jung JC, Kache R, Vines KK, Zheng YS, Bijoy P, Valluri M, Avery MA.
Jung JC, et al. Among authors: vines kk.
J Org Chem. 2004 Dec 24;69(26):9269-84. doi: 10.1021/jo048742o.
J Org Chem. 2004.
PMID: 15609966
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Syntheses of Benzo[b]furan-6-carbonitrile and 6-Cyanobenzo[b]furan-2-boronic Acid Pinacol Ester.
Williams JD, Ding X, Nguyen S, Vines KK, Peet NP.
Williams JD, et al. Among authors: vines kk.
Synth Commun. 2013;43(14):10.1080/00397911.2012.684086. doi: 10.1080/00397911.2012.684086.
Synth Commun. 2013.
PMID: 24249920
Free PMC article.
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