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Peptide inhibitors of C3 activation as a novel strategy of complement inhibition for the treatment of paroxysmal nocturnal hemoglobinuria.
Risitano AM, Ricklin D, Huang Y, Reis ES, Chen H, Ricci P, Lin Z, Pascariello C, Raia M, Sica M, Del Vecchio L, Pane F, Lupu F, Notaro R, Resuello RR, DeAngelis RA, Lambris JD. Risitano AM, et al. Among authors: sica m. Blood. 2014 Mar 27;123(13):2094-101. doi: 10.1182/blood-2013-11-536573. Epub 2014 Feb 4. Blood. 2014. PMID: 24497537 Free PMC article.
Paroxysmal nocturnal hemoglobinuria: significant association with specific HLA-A, -B, -C, and -DR alleles in an Italian population.
Lombardi ML, Terrazzano G, Cosentini E, Gargiulo L, Risitano A, Camerlingo R, Sica M, Aufiero D, Poggi A, Pirozzi G, Luzzatto L, Rotoli B, Notaro R, Alfinito F, Ruggiero G. Lombardi ML, et al. Among authors: sica m. Hum Immunol. 2008 Mar;69(3):202-6. doi: 10.1016/j.humimm.2008.02.001. Epub 2008 Mar 10. Hum Immunol. 2008. PMID: 18396213
Eculizumab treatment modifies the immune profile of PNH patients.
Alfinito F, Ruggiero G, Sica M, Udhayachandran A, Rubino V, Della Pepa R, Palatucci AT, Annunziatella M, Notaro R, Risitano AM, Terrazzano G. Alfinito F, et al. Among authors: sica m. Immunobiology. 2012 Jul;217(7):698-703. doi: 10.1016/j.imbio.2011.11.009. Epub 2011 Dec 3. Immunobiology. 2012. PMID: 22206707
The complement receptor 2/factor H fusion protein TT30 protects paroxysmal nocturnal hemoglobinuria erythrocytes from complement-mediated hemolysis and C3 fragment.
Risitano AM, Notaro R, Pascariello C, Sica M, del Vecchio L, Horvath CJ, Fridkis-Hareli M, Selleri C, Lindorfer MA, Taylor RP, Luzzatto L, Holers VM. Risitano AM, et al. Among authors: sica m. Blood. 2012 Jun 28;119(26):6307-16. doi: 10.1182/blood-2011-12-398792. Epub 2012 May 10. Blood. 2012. PMID: 22577173 Free article.
Killer immunoglobulin-like receptors (KIR) and their HLA-ligands in Italian paroxysmal nocturnal haemoglobinuria (PNH) patients.
Cosentini E, Gargiulo L, Bruno P, Lastraioli S, Risitano A, Camerlingo R, Luongo V, Serra M, Sica M, Garzillo C, Giani U, Notaro R, Alfinito F, Ruggiero G, Terrazzano G. Cosentini E, et al. Among authors: sica m. Tissue Antigens. 2012 Oct;80(4):322-7. doi: 10.1111/j.1399-0039.2012.01932.x. Epub 2012 Jul 17. Tissue Antigens. 2012. PMID: 22803950
Polymorphism of the complement receptor 1 gene correlates with the hematologic response to eculizumab in patients with paroxysmal nocturnal hemoglobinuria.
Rondelli T, Risitano AM, Peffault de Latour R, Sica M, Peruzzi B, Ricci P, Barcellini W, Iori AP, Boschetti C, Valle V, Frémeaux-Bacchi V, De Angioletti M, Socie G, Luzzatto L, Notaro R. Rondelli T, et al. Among authors: sica m. Haematologica. 2014 Feb;99(2):262-6. doi: 10.3324/haematol.2013.090001. Epub 2013 Sep 13. Haematologica. 2014. PMID: 24038027 Free PMC article. Clinical Trial.
149 results