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Admixture facilitates genetic adaptations to high altitude in Tibet.
Jeong C, Alkorta-Aranburu G, Basnyat B, Neupane M, Witonsky DB, Pritchard JK, Beall CM, Di Rienzo A. Jeong C, et al. Among authors: pritchard jk. Nat Commun. 2014;5:3281. doi: 10.1038/ncomms4281. Nat Commun. 2014. PMID: 24513612 Free PMC article.
Adaptation - not by sweeps alone.
Pritchard JK, Di Rienzo A. Pritchard JK, et al. Nat Rev Genet. 2010 Oct;11(10):665-7. doi: 10.1038/nrg2880. Epub 2010 Sep 14. Nat Rev Genet. 2010. PMID: 20838407 Free PMC article.
Adaptations to climate-mediated selective pressures in humans.
Hancock AM, Witonsky DB, Alkorta-Aranburu G, Beall CM, Gebremedhin A, Sukernik R, Utermann G, Pritchard JK, Coop G, Di Rienzo A. Hancock AM, et al. Among authors: pritchard jk. PLoS Genet. 2011 Apr;7(4):e1001375. doi: 10.1371/journal.pgen.1001375. Epub 2011 Apr 21. PLoS Genet. 2011. PMID: 21533023 Free PMC article.
DNase I sensitivity QTLs are a major determinant of human expression variation.
Degner JF, Pai AA, Pique-Regi R, Veyrieras JB, Gaffney DJ, Pickrell JK, De Leon S, Michelini K, Lewellen N, Crawford GE, Stephens M, Gilad Y, Pritchard JK. Degner JF, et al. Among authors: pritchard jk. Nature. 2012 Feb 5;482(7385):390-4. doi: 10.1038/nature10808. Nature. 2012. PMID: 22307276 Free PMC article.
The genetic architecture of adaptations to high altitude in Ethiopia.
Alkorta-Aranburu G, Beall CM, Witonsky DB, Gebremedhin A, Pritchard JK, Di Rienzo A. Alkorta-Aranburu G, et al. Among authors: pritchard jk. PLoS Genet. 2012;8(12):e1003110. doi: 10.1371/journal.pgen.1003110. Epub 2012 Dec 6. PLoS Genet. 2012. PMID: 23236293 Free PMC article.
189 results