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Tuning glycosidase inhibition through aglycone interactions: pharmacological chaperones for Fabry disease and GM1 gangliosidosis.
Aguilar-Moncayo M, Takai T, Higaki K, Mena-Barragán T, Hirano Y, Yura K, Li L, Yu Y, Ninomiya H, García-Moreno MI, Ishii S, Sakakibara Y, Ohno K, Nanba E, Ortiz Mellet C, García Fernández JM, Suzuki Y. Aguilar-Moncayo M, et al. Among authors: ortiz mellet c. Chem Commun (Camb). 2012 Jul 4;48(52):6514-6. doi: 10.1039/c2cc32065g. Epub 2012 May 23. Chem Commun (Camb). 2012. PMID: 22618082
Inhibitor versus chaperone behaviour of d-fagomine, DAB and LAB sp(2)-iminosugar conjugates against glycosidases: A structure-activity relationship study in Gaucher fibroblasts.
Mena-Barragán T, García-Moreno MI, Nanba E, Higaki K, Concia AL, Clapés P, García Fernández JM, Ortiz Mellet C. Mena-Barragán T, et al. Among authors: ortiz mellet c. Eur J Med Chem. 2016 Oct 4;121:880-891. doi: 10.1016/j.ejmech.2015.08.038. Epub 2015 Aug 31. Eur J Med Chem. 2016. PMID: 26361824
148 results