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Determination of an optimal dosing regimen for fexinidazole, a novel oral drug for the treatment of human African trypanosomiasis: first-in-human studies.
Clin Pharmacokinet. 2014 Jun;53(6):565-80. doi: 10.1007/s40262-014-0136-3.
Clin Pharmacokinet. 2014.
PMID: 24535888
Free PMC article.
Clinical Trial.
Oral fexinidazole for late-stage African Trypanosoma brucei gambiense trypanosomiasis: a pivotal multicentre, randomised, non-inferiority trial.
Mesu VKBK, Kalonji WM, Bardonneau C, Mordt OV, Blesson S, Simon F, Delhomme S, Bernhard S, Kuziena W, Lubaki JF, Vuvu SL, Ngima PN, Mbembo HM, Ilunga M, Bonama AK, Heradi JA, Solomo JLL, Mandula G, Badibabi LK, Dama FR, Lukula PK, Tete DN, Lumbala C, Scherrer B, Strub-Wourgaft N, Tarral A.
Mesu VKBK, et al. Among authors: mordt ov.
Lancet. 2018 Jan 13;391(10116):144-154. doi: 10.1016/S0140-6736(17)32758-7. Epub 2017 Nov 4.
Lancet. 2018.
PMID: 29113731
Clinical Trial.
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A DBS method for quantitation of the new oral trypanocidal drug fexinidazole and its active metabolites.
Filali-Ansary A, Augé C, Abgrall A, Souchaud M, Pellissier F, Mordt OV, Blesson S, Sanderink GJ.
Filali-Ansary A, et al. Among authors: mordt ov.
Bioanalysis. 2016 Oct;8(19):2045-63. doi: 10.4155/bio-2016-0110. Epub 2016 Sep 9.
Bioanalysis. 2016.
PMID: 27611920
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In-hospital safety in field conditions of nifurtimox eflornithine combination therapy (NECT) for T. b. gambiense sleeping sickness.
Schmid C, Kuemmerle A, Blum J, Ghabri S, Kande V, Mutombo W, Ilunga M, Lumpungu I, Mutanda S, Nganzobo P, Tete D, Mubwa N, Kisala M, Blesson S, Mordt OV.
Schmid C, et al. Among authors: mordt ov.
PLoS Negl Trop Dis. 2012;6(11):e1920. doi: 10.1371/journal.pntd.0001920. Epub 2012 Nov 29.
PLoS Negl Trop Dis. 2012.
PMID: 23209861
Free PMC article.
Clinical Trial.
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