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Microfluidic, marker-free isolation of circulating tumor cells from blood samples.
Karabacak NM, Spuhler PS, Fachin F, Lim EJ, Pai V, Ozkumur E, Martel JM, Kojic N, Smith K, Chen PI, Yang J, Hwang H, Morgan B, Trautwein J, Barber TA, Stott SL, Maheswaran S, Kapur R, Haber DA, Toner M. Karabacak NM, et al. Among authors: kapur r. Nat Protoc. 2014 Mar;9(3):694-710. doi: 10.1038/nprot.2014.044. Epub 2014 Feb 27. Nat Protoc. 2014. PMID: 24577360 Free PMC article.
Inertial focusing for tumor antigen-dependent and -independent sorting of rare circulating tumor cells.
Ozkumur E, Shah AM, Ciciliano JC, Emmink BL, Miyamoto DT, Brachtel E, Yu M, Chen PI, Morgan B, Trautwein J, Kimura A, Sengupta S, Stott SL, Karabacak NM, Barber TA, Walsh JR, Smith K, Spuhler PS, Sullivan JP, Lee RJ, Ting DT, Luo X, Shaw AT, Bardia A, Sequist LV, Louis DN, Maheswaran S, Kapur R, Haber DA, Toner M. Ozkumur E, et al. Among authors: kapur r. Sci Transl Med. 2013 Apr 3;5(179):179ra47. doi: 10.1126/scitranslmed.3005616. Sci Transl Med. 2013. PMID: 23552373 Free PMC article.
A microfluidic device for label-free, physical capture of circulating tumor cell clusters.
Sarioglu AF, Aceto N, Kojic N, Donaldson MC, Zeinali M, Hamza B, Engstrom A, Zhu H, Sundaresan TK, Miyamoto DT, Luo X, Bardia A, Wittner BS, Ramaswamy S, Shioda T, Ting DT, Stott SL, Kapur R, Maheswaran S, Haber DA, Toner M. Sarioglu AF, et al. Among authors: kapur r. Nat Methods. 2015 Jul;12(7):685-91. doi: 10.1038/nmeth.3404. Epub 2015 May 18. Nat Methods. 2015. PMID: 25984697 Free PMC article.
Continuous Flow Microfluidic Bioparticle Concentrator.
Martel JM, Smith KC, Dlamini M, Pletcher K, Yang J, Karabacak M, Haber DA, Kapur R, Toner M. Martel JM, et al. Among authors: kapur r. Sci Rep. 2015 Jun 10;5:11300. doi: 10.1038/srep11300. Sci Rep. 2015. PMID: 26061253 Free PMC article.
HER2 expression identifies dynamic functional states within circulating breast cancer cells.
Jordan NV, Bardia A, Wittner BS, Benes C, Ligorio M, Zheng Y, Yu M, Sundaresan TK, Licausi JA, Desai R, O'Keefe RM, Ebright RY, Boukhali M, Sil S, Onozato ML, Iafrate AJ, Kapur R, Sgroi D, Ting DT, Toner M, Ramaswamy S, Haas W, Maheswaran S, Haber DA. Jordan NV, et al. Among authors: kapur r. Nature. 2016 Sep 1;537(7618):102-106. doi: 10.1038/nature19328. Epub 2016 Aug 24. Nature. 2016. PMID: 27556950 Free PMC article.
Monolithic Chip for High-throughput Blood Cell Depletion to Sort Rare Circulating Tumor Cells.
Fachin F, Spuhler P, Martel-Foley JM, Edd JF, Barber TA, Walsh J, Karabacak M, Pai V, Yu M, Smith K, Hwang H, Yang J, Shah S, Yarmush R, Sequist LV, Stott SL, Maheswaran S, Haber DA, Kapur R, Toner M. Fachin F, et al. Among authors: kapur r. Sci Rep. 2017 Sep 7;7(1):10936. doi: 10.1038/s41598-017-11119-x. Sci Rep. 2017. PMID: 28883519 Free PMC article.
Microfluidic concentration and separation of circulating tumor cell clusters from large blood volumes.
Edd JF, Mishra A, Dubash TD, Herrera S, Mohammad R, Williams EK, Hong X, Mutlu BR, Walsh JR, Machado de Carvalho F, Aldikacti B, Nieman LT, Stott SL, Kapur R, Maheswaran S, Haber DA, Toner M. Edd JF, et al. Among authors: kapur r. Lab Chip. 2020 Feb 7;20(3):558-567. doi: 10.1039/c9lc01122f. Epub 2020 Jan 14. Lab Chip. 2020. PMID: 31934715 Free PMC article.
Ultrahigh-throughput magnetic sorting of large blood volumes for epitope-agnostic isolation of circulating tumor cells.
Mishra A, Dubash TD, Edd JF, Jewett MK, Garre SG, Karabacak NM, Rabe DC, Mutlu BR, Walsh JR, Kapur R, Stott SL, Maheswaran S, Haber DA, Toner M. Mishra A, et al. Among authors: kapur r. Proc Natl Acad Sci U S A. 2020 Jul 21;117(29):16839-16847. doi: 10.1073/pnas.2006388117. Epub 2020 Jul 8. Proc Natl Acad Sci U S A. 2020. PMID: 32641515 Free PMC article.
Isolation of circulating tumor cells.
Edd JF, Mishra A, Smith KC, Kapur R, Maheswaran S, Haber DA, Toner M. Edd JF, et al. Among authors: kapur r. iScience. 2022 Jul 1;25(8):104696. doi: 10.1016/j.isci.2022.104696. eCollection 2022 Aug 19. iScience. 2022. PMID: 35880043 Free PMC article. Review.
640 results